Sökning: "Deliverable treatment plans"

Hittade 5 avhandlingar innehållade orden Deliverable treatment plans.

  1. 1. On Quality in Radiotherapy Treatment Plan Optimisation

    Författare :Hunor Benedek; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pareto optimisation; Pareto fronts; Dose prediction; Machine learning; Deliverable treatment plans; Volumetric modulated arc therapy; IMRT; patient-specific plan quality; plan quality; Multi Criteria Optimisation; Automated Treatment Planning;

    Sammanfattning : Radiotherapy is one of the essential treatments used in the fight against cancer. The goal of radiotherapy is to deliver a high dose of ionising radiation to the tumour volume and at the same time minimise the effect on healthy tissue by reducing the radiation to critical organs. LÄS MER

  3. 2. Multicriteria optimization for managing tradeoffs in radiation therapy treatment planning

    Författare :Rasmus Bokrantz; Anders Forsgren; Karl-Heinz Küfer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; multicriteria optimization; robust optimization; Pareto optimality; Pareto surface approximation; Pareto surface navigation; intensity-modulated radiation therapy; volumetric-modulated arc therapy; intensity-modulated proton therapy; Optimering; flermålsoptimering; robust optimering; Paretooptimalitet; Paretofrontsapproximation; Paretofrontsnavigering; intensitetsmodulerad strålterapi; rotationsterapi; intensitetsmodulerad protonterapi;

    Sammanfattning : Treatment planning for radiation therapy inherently involves tradeoffs, such as between tumor control and normal tissue sparing, between time-efficiency and dose quality, and between nominal plan quality and robustness. The purpose of this thesis is to develop methods that can facilitate decision making related to such tradeoffs. LÄS MER

  4. 3. Clinical application of intensity and energy modulated radiotherapy with photon and electron beams

    Författare :Xiangkui Mu; Björn Zackrisson; Mikael Karlsson; Thomas Björk-Eriksson; Erik Blomquist; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; IMXT; IMET; IMPT; proton beams; electron beams; treatment planning; cancer induction; side-effects; fraction time; intensity modulated radiotherapy; Onkologi; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : In modern, advanced radiotherapy (e.g. intensity modulated photon radiotherapy, IMXT) the delivery time for each fraction becomes prolonged to 10-20 minutes compared with the conventional, commonly 2-5 minutes. The biological effect of this prolongation is not fully known. LÄS MER

  5. 4. Utilizing Problem Structure in Optimization of Radiation Therapy

    Författare :Fredrik Carlsson; Anders Forsgren; Edwin Romeijn; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; intensity-modulated radiation therapy; conjugate-gradient method; step-and-shoot delivery; column generation; quasi-Newton method; regularization; sequential quadratic programming; Optimization; systems theory; Optimeringslära; systemteori;

    Sammanfattning : In this thesis, optimization approaches for intensity-modulated radiation therapy are developed and evaluated with focus on numerical efficiency and treatment delivery aspects. The first two papers deal with strategies for solving fluence map optimization problems efficiently while avoiding solutions with jagged fluence profiles. LÄS MER

  7. 5. Robust optimization of radiation therapy accounting for geometric uncertainty

    Författare :Albin Fredriksson; Anders Forsgren; Timothy C. Y. Chan; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; intensity-modulated proton therapy; uncertainty; robust planning; setup error; range error; intensity-modulated radiation therapy; multicriteria optimization;

    Sammanfattning : Geometric errors may compromise the quality of radiation therapy treatments. Optimization methods that account for errors can reduce their effects.The first paper of this thesis introduces minimax optimization to account for systematic range and setup errors in intensity-modulated proton therapy. LÄS MER