Sökning: "Degree of methylation"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Degree of methylation.

  1. 1. Array-based Characterization of Chronic Lymphocytic Leukemia : - with Focus on Subsets Carrying Stereotyped B-cell Receptors

    Författare :Millaray Marincevic; Richard Rosenquist; Andreas Rosenwald; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic lymphocytic leukemia; array-based characterization; stereotyped B-cell receptors; subsets; antigens; SNP array; gene expression array; methylation array; Clinical genetics; Klinisk genetik; Clinical Genetics; Klinisk genetik;

    Sammanfattning : In chronic lymphocytic leukemia (CLL), the presence of multiple subsets expressing ‘stereotyped’ B-cell receptors (BCRs) has implicated antigen(s) in leukemogenesis. These stereotyped subsets display similar immunoglobulin (IG) gene usage, almost identical complementarity determining region 3’s and may share clinical features. LÄS MER

  3. 2. Unravelling Mechanistic Insights of Eukaryotic Transcriptional Control

    Författare :Johanna Hörberg; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcriptional control; Gene expression regulation; DNA supercoiling; DNA methylation; DNA-protein recognition; Basic-Leucine-Zipper transcription factors; Basic-Helix-Loop-Helix transcription factors; Sequence specific DNA plasticity; Transcription factor cooperativity; Cancer; Molecular modelling; Molecular dynamics;

    Sammanfattning : DNA transcription involves the association of multiple proteins with DNA to convert the genetic information into messenger-RNA transcripts, which later will be translated into proteins. Con-trolled regulation of transcription is imperative for preserving the healthy and homeostatic state of cells. LÄS MER

  4. 3. Ecological and biogeochemical implications of the recovery of Eurasian beavers

    Författare :Oded Levanoni; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In pre-industrial times beavers, ecosystem engineers, inhabited most of the Holarctic. Intensive exploitation over the last millennium, particularly in Europe during the 18th and 19th centuries, led to a dramatic decline in beaver populations. LÄS MER

  5. 4. Quantitative genetics of gene expression and methylation in the chicken

    Författare :Andrey Höglund; Dominic Wright; Per Jensen; Rie Henriksen; Kees van Oers; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In quantitative genetics the relationship between genetic and phenotypic variation is investigated. The identification of these variants can bring improvements to selective breeding, allow for transgenic techniques to be applied in agricultural settings and assess the risk of polygenic diseases. LÄS MER

  7. 5. Spectroscopic data and multivariate analysis : tools to study genetic perturbations in poplar trees

    Författare :Susanne Wiklund; Ulf Edlund; Olav Kvalheim; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; Metabolomics; Degree of methylation; S-plot; SUS-plot; Metabonomics; Poplar; MLR; PLS; OPLS; PCA; Pectin; Wood; Organic chemistry; Organisk kemi;

    Sammanfattning : In our society in the 21st century one of the greatest challenges is to provide raw materials to the industry in a sustainable way. This requires increased use of renewable raw materials such as wood. Wood is widely used in pulp, paper and textile industries and ongoing research efforts aim to extend the use of wood in e.g. LÄS MER