Sökning: "Degenerative disease"
Visar resultat 1 - 5 av 83 avhandlingar innehållade orden Degenerative disease.
1. Genomic strategies towards the dissection of human complex disease
Sammanfattning : Complex diseases are caused by the activities of many genes acting in concert with environmental factors. A major challenge facing human genetic research is to unravel the genetic factors behind complex disorders. LÄS MER
2. Novel Pharmacometric Methods for Design and Analysis of Disease Progression Studies
Sammanfattning : With societies aging all around the world, the global burden of degenerative diseases is expected to increase exponentially. From the perspective drug development, degenerative diseases represent an especially challenging class. LÄS MER
3. Mitochondrial dysfunction in ageing and degenerative disease
Sammanfattning : The cytoplasm of eukaryotic cells contains a dynamic network of double-membraned organelles, called mitochondria, which perform the process of oxidative phosphorylation (OXPHOS) that provides cellular energy in the form of ATP. The respiratory chain creates an electrochemical gradient across the inner mitochondrial membrane, which drives ATP synthesis by the ATP synthase. LÄS MER
4. Inflammatory and degenerative disease in the temporomandibular joint
Sammanfattning : Temporomandibular joint (TMJ) arthroscopy is an established technique with high diagnostic accuracy regarding synovitis and degenerative changes of the articular fibrocartilage and disk. However, so far no studies have been done to correlate the macroscopic and histologic findings with each arthroscopic criterion. LÄS MER
5. Outcome after surgery for isthmic spondylolisthesis and degenerative disc disease
Sammanfattning : Individuals with isthmic spondylolisthesis and lumbar degenerative disc disease may have low back and leg pain. Those with persistent symptoms non-responsive to conservative treatment are sometimes treated surgically. Various surgical methods have been introduced, but long-term outcome comparisons are scarce. LÄS MER