Sökning: "Deacetylation"
Visar resultat 1 - 5 av 24 avhandlingar innehållade ordet Deacetylation.
1. Protein Acetylation – A Multifunctional Regulator of TGF-β Signaling
Sammanfattning : Transforming growth factor β (TGF-β) is a member of a large family of cytokines that regulate many crucial events in cells, including proliferation, differentiation, migration and apoptosis. Deregulated TGF-β signaling is associated with various forms of cancers and developmental disorders. LÄS MER
2. Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain
Sammanfattning : The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. LÄS MER
3. Chemical studies of 0-antigens from Shigella
Sammanfattning : The structure of 13 types of Shigella flexneri O-antigens has been determined, using a N-deacetylation-deamination reaction sequence. The correlation between chemical structures and immunological classification of Shigella flexneri is discussed. LÄS MER
4. N-Sulfation and Polymerization in Heparan Sulfate Biosynthesis
Sammanfattning : Heparan sulfate (HS) is a glycosaminoglycan present in all cell types covalently attached to core proteins forming proteoglycans. HS interacts with different proteins and thereby affects a variety of processes. LÄS MER
5. Characterisation of CtBP : A Co-Repressor of Transcription that Interacts with the Adenovirus E1A Protein
Sammanfattning : In this study, adenovirus E1A has been used to target and analyse the transcriptional function of the cellular C-terminal Binding Protein (CtBP).Transcription is a complex biochemical process that represents a major regulatory step in gene expression. LÄS MER