Sökning: "David Haage"

Hittade 1 avhandling innehållade orden David Haage.

1. 1. Sex and stress steroid modulation of GABA mediated chloride ion flux in rat CNS

   Författare :Jessica Strömberg; Per Lundgren; Torbjörn Bäckström; David Haage; Esa Korpi; Umeå universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; allopregnanolone; chloride ion uptake; patch-clamp; 3beta-steroids; kinetic parameters; rat brain; Obstetrics and gynaecology; Obstetrik och gynekologi;

   Sammanfattning : Background: Sex and stress steroids are metabolized to 3a-hydroxy-pregnane-steroid metabolites such as allopregnanolone (Allo) and tetrahydrodeoxycorticosterone (THDOC). Allo and THDOC are neuroactive steroids that are metabolized in the brain and act in brain as potent positive GABAA receptor function modulators. LÄS MER