Sökning: "David Engblom"

Visar resultat 16 - 17 av 17 avhandlingar innehållade orden David Engblom.

  1. 16. Functional Characterization of Centrally Expressed Solute Carriers and G Protein-Coupled Receptors

    Författare :Smitha Sreedharan; Helgi Schiöth; Robert Fredriksson; David Engblom; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GPCR; SLC; Gpr153; Gpr162; Slc17; Slc38; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Sammanfattning : Transmembrane proteins are gatekeepers of the cells; controlling the transport of substrates as well as communicating signals among cells and between the organelles and cytosol. Solute carriers (SLC) and G protein-coupled receptors (GPCR) are the largest family of membrane transporters and membrane receptors respectively. LÄS MER

  3. 17. Interactions between the brain and the immune system in pain and inflammation

    Författare :Joanna Zajdel; David Engblom; Annika Thorsell; Jan Pieter Konsman; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; pain; EP3Rs; serotonin; CGRP; conditioned taste aversion; maternal separation; maternal buffering;

    Sammanfattning : Reciprocal interactions between the nervous and immune systems have gained a lot of attention in the last two decades, especially after demonstrating that cytokine immunotherapies can induce depression and after describing the inflammatory reflex. A lot of effort has been dedicated to understanding how the signals from the immune system reach the brain and vice versa, and on their role in health and disease. LÄS MER