Sökning: "David A Kendall"

Hittade 1 avhandling innehållade orden David A Kendall.

  1. 1. The cellular processing of the endocannabinoid anandamide and its pharmacological manipulation

    Författare :Lina Thors; Christopher J Fowler; David A Kendall; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocannabinoid; anandamide; cellular processing; pain; flavonoids; fatty acid amide hydrolase; Pharmacology; Farmakologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert most of their actions by binding to cannabinoid receptors. The effects of the endocannabinoids are short-lived due to rapid cellular accumulation and metabolism, for AEA, primarily by the enzymes fatty acid amide hydrolase (FAAH). LÄS MER