Sökning: "Dan Lindholm"

Hittade 4 avhandlingar innehållade orden Dan Lindholm.

  1. 1. Hormonal Regulation of Neural Stem Cell Proliferation and Fate Determination

    Författare :Karin Brännvall; Dan Lindholm; Sandra Ceccatelli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neural stem cell; Proliferation; Fate determination; Hormones; Anabolic androgenic steroids; Neurovetenskap; Neurology; Neurologi;

    Sammanfattning : Stem cells have the capacity for both self renewal, and to form all cell types in the body. Interestingly, so called neural stem cells (NSCs) are found in the adult human brain, which is of significance both out of a developmental perspective and from a clinical point of view. LÄS MER

  3. 2. Cross-linked Profilin:actin - A tool to study actin dynamics in non-muscle cells

    Författare :Staffan Grenklo; Roger Karlsson; Dan Lindholm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; actin dynamics; profilin; actin; Profilin-actin complex; Cell motility; synaptic vesicle trafficing; Far western; fluorescence microscopy; Cell biology; Cellbiologi;

    Sammanfattning : The microfilament system, consisting of actin and a number of auxiliary proteins, is fundamental for cell motility. Its dynamic organization depends on receptor-mediated signals, leading to rapid polymerizations and depolymerizations of actin. LÄS MER

  4. 3. Novel Interactors of X-linked Inhibitor of Apoptosis Protein : Expression and Effects on Tumor Cell Death

    Författare :Håkan Steen; Dan Lindholm; Bertrand Joseph; Uppsala universitet; []
    Nyckelord :Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

    Sammanfattning : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. LÄS MER

  5. 4. Amyotrophic Lateral Sclerosis – A Study in Transgenic Mice

    Författare :Hanna Wootz; Dan Lindholm; Håkan Aldskogius; Christopher Fowler; Uppsala universitet; []
    Nyckelord :Neurosciences; ALS; Caspase; Caspase-12; Cathepsin; Cystatin; ER stress; Motor neuron; Neurodegeneration; Sod1; XIAP; Neurovetenskap;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an incidence of 1.5-2.7/100000 people/year. Today there is no cure for the disease and only symptomatic treatments are available. LÄS MER