Sökning: "Dan Hultmark"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Dan Hultmark.

  1. 1. Nora virus as a model to study persistent infection in Drosophila melanogaster

    Författare :Mazen Habayeb; Dan Hultmark; Joachim De Miranda; Molecular Biology; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophial; persistence; transmission; RNAi; capsid proteins; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; molekylärbiologi; Molecular Biology;

    Sammanfattning : Drosophila melanogaster has been widely used as a model organism to study the immune responses against bacteria, fungi, parasites and viruses. Here, I present a D. melanogaster virus as a model to study persistent virus infections. I have discovered and characterized the Nora virus, a small picorna-like RNA virus able to persistently infect D. LÄS MER

  2. 2. Insect immunity : Inducible antibacterial proteins from Hyalophora cecropia

    Författare :Dan Hultmark; Hans Boman; Sten Hammarström; mikrobiologiska institutionen Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; immunologi; Immunology;

    Sammanfattning : A powerful bactericidal activity can be induced in the hemolymph of many insects as a response to an injection of bacteria. The nature of the effector molecules of this immune response was investigated, using pupae of the Cecropia moth, Hyalophora cecropia. LÄS MER

  3. 3. Activation of the Cellular Immune Response in Drosophila melanogaster Larvae

    Författare :Ines Anderl; Dan Hultmark; Paul Badenhorst; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; immunity; blood cells; hematopoiesis; flow cytometry; in vivo imaging; genetic screens; Tl10b; fat body; Toll signaling; molekylärbiologi; Molecular Biology;

    Sammanfattning : During the last 40 years, Drosophila melanogaster has become an invaluable tool in understanding innate immunity. The innate immune system of Drosophila consists of a humoral and a cellular component. While many details are known about the humoral immune system, our knowledge about the cellular immune system is comparatively small. LÄS MER

  4. 4. Communicate or die : signalling in Drosophila immunity

    Författare :Karin Borge-Renberg; Dan Hultmark; Michéle Crozatier; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drosophila; innate immunity; PGRP-LC; pattern recognition; JNK; antimicrobial peptides; Molecular biology; Molekylärbiologi;

    Sammanfattning : In general the work behind this thesis has revolved around the interesting pattern recognition gene family PGRPs (peptidoglycan recognition proteins). In particular the transmembrane PGRP-LC and to investigate its multifaceted role in the immune response of the fruit fly. LÄS MER

  5. 5. Biology of a small RNA virus that infects Drosophila melanogaster

    Författare :Sajna Anand Sadanandan; Dan Hultmark; Francis Jiggins; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophila melanogaster; virus biology; host-pathogen interaction; molekylärbiologi; Molecular Biology;

    Sammanfattning : Drosophila melanogaster has been extensively used as a model organism to study diverse facets of biology, including host-pathogen interactions and the basic biology of its pathogens. I have used the fruit fly as a model to study elementary aspects of Nora virus biology, such as the role of the different proteins encoded by the virus genome. LÄS MER