Sökning: "DNA-bending sequence"

Hittade 3 avhandlingar innehållade orden DNA-bending sequence.

  1. 1. Nucleosome positioning : impact on transcription factors access

    Författare :Qiao Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :glucocorticoid receptor; transcription factor; gene regulation; nucleosome; nucleosome positioning; DNA-bending sequence;

    Sammanfattning : In the eukaryotic cell nucleus, DNA is organized into nucleosomes. Some of the regulatory regions are integrated into sequence-specifically positioned nucleosomes. LÄS MER

  2. 2. Transcription factor effects on chromatin organisation and gene regulation

    Författare :Per-Henrik Holmqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chromatin; enhanceosome; MMTV; GR; NF1; Oct1; FoxA;

    Sammanfattning : The intranuclear DNA of all eukaryotic cells is packed into chromatin, generating a repressive environment for the genome. Remodelling of the local chromatin structure is a vital process that allows access to the obscured DNA sequence and may induce the expression of specific genes. LÄS MER

  3. 3. Regulation of HIV-1 provirus transcription

    Författare :Mojgan H Naghavi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Key words- HIV-1; LTR; transcription; subtypes; phylogenetic analysis; NFkappaB; USF; MCEF; HMG-1 DSP1; Dorsal.;

    Sammanfattning : Transcription of the HIV-genome is regulated by the interaction of viral long terminal repeat (LTR) cis-acting sequences with a complex of viral regulatory proteins and cellular transcription factors. The complex interplay between the cellular-, and/or viral proteins and LTR of different subtypes may play a role in the control of HIV-1 latency versus activation. LÄS MER