Sökning: "DNA polymerase eta"

Hittade 2 avhandlingar innehållade orden DNA polymerase eta.

  1. 1. Ribonucleotides in DNA - Application in genome-wide DNA polymerase tracking and physiological role in eukaryotes

    Författare :Katrin Kreisel; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ribonucleotides; DNA instability; DNA polymerase eta; nuclear DNA; mitochondrial DNA;

    Sammanfattning : The genetic code in the eukaryotic cell is stored in the form of DNA, which is more resistant to hydrolysis than RNA. Replication fidelity and DNA repair mechanisms are in place to ensure genomic integrity to preserve the information encoded. LÄS MER

  2. 2. Understanding the role and regulation of Polη for damage-induced cohesion

    Författare :Pei-Shang Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In response to DSBs, de novo sister chromatid cohesion can be established after DNA replication in Saccharomyces cerevisiae. The damage-induced cohesion is formed close to the break and genome-wide on undamaged chromosomes. LÄS MER