Sökning: "DNA mixtures"
Visar resultat 1 - 5 av 26 avhandlingar innehållade orden DNA mixtures.
1. Mitochondrial DNA in Sensitive Forensic Analysis
Sammanfattning : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. LÄS MER
2. Competitive-Binding Based Optical DNA Mapping - From Bacterial Plasmids to the Human Genome
Sammanfattning : Significant advances within the field of DNA sequencing have allowed us to study DNA at a level of detail that was previously impossible. However, dynamic genomic regions with a high degree of structural variations, while being linked to disease in humans and increased resistance to antibiotics, are still challenging to characterize. LÄS MER
3. Sensitive Identification Tools in Forensic DNA Analysis
Sammanfattning : DNA as forensic evidence is valuable in criminal investigations. Implementation of new, sensitive and fast technologies is an important part of forensic genetic research. This thesis aims to evaluate new sensitive methods to apply in forensic DNA analysis including analysis of old skeletal remains. LÄS MER
4. Markets, mixtures and molecular methods : Investigating medicinal plant and edible orchid diversity in Tanzania and Zambia
Sammanfattning : Medicinal plants are an important source of primary healthcare for many people in Tanzania. These medicinal plants are harvested from the wild, and increasing commercial trade poses a serious threat to local plant populations. Currently it is unknown which species are traded and in what amounts. LÄS MER
5. Impact of epidemiologically identified mixtures of endocrine disrupting chemicals on metabolic programming
Sammanfattning : We are ubiquitously exposed to a plethora of endocrine-disrupting chemicals (EDCs), i.e. substances that alter the function(s) of the endocrine system. While ample evidence show individual EDC's influence on developmental processes resulting in adverse health outcomes, less is known about the effects of human-relevant EDC mixtures exposure. LÄS MER