Sökning: "DNA lesion"
Visar resultat 1 - 5 av 38 avhandlingar innehållade orden DNA lesion.
- Detta är en avhandling från Umeå : Medicinsk kemi och biofysik
Sammanfattning : To transfer the information in the genome from mother cell to daughter cell, the DNA replication must be carried out only once and with very high fidelity prior to every cell division. In yeast there are several different DNA polymerases involved in DNA replication and/or DNA repair. LÄS MER
- Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : Generation of DNA damage is regarded to be an important initial event in the development cancer. Consequently, a battery of tests have been developed to detect different types of genotoxic effects in order to be able to predict the potential genotoxicity and mutagenicity of chemicals, including both pharmaceutical drugs and various types of environmental and occupational agents, as well as dietary factors. LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, Biosciences and Nutrition
Sammanfattning : Ultraviolet radiation is considered to be the most harmful part of solar energy affecting man. The depletion of the ozone layer around the Earth increases the total exposure to UV-light. The incidence of skin cancer in man has been shown to be associated with exposure to solar radiation, especially to UV-light. LÄS MER
4. Quantum Chemical Studies of Protein-Bound Chromophores, UV-Light Induced DNA Damages, and Lignin FormationDetta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : Quantum chemical methods have been used to provide a better understanding of the photochemistry of astaxanthin and phytochromobilin; the photoenzymic repair of UV-light induced DNA damages; and the formation of lignin. The carotenoid astaxanthin (AXT) is responsible for the colouration of lobster shell. LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, false
Sammanfattning : Studies on DNA Adducts and Carcinogenesis with 2-Nitrofluorene as a Model Substance Xian-Shu Cui Center for Nutrition and Toxicology Department of Biosciences at Novum, Karolinska institute Novum, S-141 57 Huddinge, Sweden A number of carcinogens or their electrophilic intermediates are able to bind covalently to DNA, forming DNA adducts. DNA adducts may cause gene mutations if they are misrepaired or remain unrepaired before DNA replication occurs. LÄS MER