Sökning: "DNA detection methods"

Visar resultat 26 - 30 av 169 avhandlingar innehållade orden DNA detection methods.

  1. 26. Gene Expression in Cancer Cells : Detection of Splice Variants, Allele-specific Expression and DNA Methylation

    Författare :Lili Milani; Ann-Christine Syvänen; Thomas R. Gingeras; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : The human genome sequencing project has provided a wealth of information on sequence variation between individuals. The surprisingly low number of genes in the human genome is compensated for by a complex regulation of gene expression. LÄS MER

  2. 27. Molecular Genetic Studies of the Blood Group ABO Locus in Man

    Författare :Martin L Olsson; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chi sequence; recombination; population studies; blood group serology; erythrocyte; blood transfusion; sequencing; DNA; PCR; genomic; Blood group ABO; allele; Immunology; serology; transplantation; Immunologi; serologi; Clinical genetics; Klinisk genetik;

    Sammanfattning : The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. LÄS MER

  3. 28. Improved Techniques for High-Throughput Molecular Diagnostics

    Författare :Mario Curcio; KTH; []
    Nyckelord :DNA; Molecular Diagnostics;

    Sammanfattning : The amount of information derived from sequencing the humangenome is leading to an exponential increase in the rate atwhich genes and genetic disorders are mapped and characterized.As a consequence, the demand for genetic testing is alsodramatically increasing. LÄS MER

  4. 29. Long-term survival and prognostic factors in endometrial cancer - a populationbased cohort study

    Författare :Teresia Svanvik; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; relative survival; DNA ploidy; s-phase fraction; p53; socioeconomic inequality; early detection;

    Sammanfattning : Aims: The over-all aims of this thesis were to evaluate the associations between prognostic factors and excess mortality rate, between socioeconomic and immigrant status and incidence rate, in endometrioid (EEC) and non-endometrioid (NEC) endometrial carcinoma. Material and methods: Study I-III were retrospective population-based cohort studies including women resident in a defined geographical area, with endometrial carcinoma. LÄS MER

  5. 30. DNA Tools and Microfluidic Systems for Molecular Analysis

    Författare :Jonas Jarvius; Ulf Landegren; Mats Nilsson; P Luke Lee; Uppsala universitet; []
    Nyckelord :Molecular medicine; Proximity ligation; Microfluidics; Single molecule detection; Microarray; Bonding; Molekylärmedicin;

    Sammanfattning : Improved methods are needed to interrogate the genome and the proteome. Methods with high selectivity, wide dynamic range, and excellent precision, capable of simultaneously analyzing many biomolecules are required to decipher cellular function. This thesis describes a molecular and microfluidic toolbox designed with those criteria in mind. LÄS MER