Sökning: "DNA breathing dynamics"

Hittade 2 avhandlingar innehållade orden DNA breathing dynamics.

1. 1. Promoter Engineering for Cyanobacteria : An Essential Step

   Författare :Hsin-Ho Huang; Peter Lindblad; James Golden; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; synthetic biology; cyanobacteria; promoter; engineering; TetR; DNA breathing dynamics; transcription; regulation;

   Sammanfattning : Synthetic biology views a complex biological system as an ensemble in the hierarchy of parts, devices, systems, and networks. The practice of using engineering rules such as decoupling and standardization to understand, predict, and re-build novel biological functions from model-driven designed genetic circuits is emphasized. LÄS MER

3. 2. A biophysical study of nucleic acid interactions with analogues and drugs

   Författare :Ulrica Sehlstedt; Donald M Crothers; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleic acids; binding modes; polarised light spectroscopy; linear dichroism; NMR; triple helix; base-pair breathing dynamics; DAPI; porphyrins; quinoxaline derivatives; Biophysics; Biofysik; Biophysics; biofysik;

   Sammanfattning : work presented in this thesis concerns studies on the physicochemical nature of interactions between nucleic acids and small ligands. The outcome of such studies can yield insights at a molecular level into the physiological mechanisms of action of biologically active nucleic-acid binding molecules. LÄS MER