Sökning: "DNA biosynthesis"

Visar resultat 6 - 10 av 74 avhandlingar innehållade orden DNA biosynthesis.

  1. 6. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides

    Författare :Jianhui Rong; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; 2-O-sulphotransferase; neo-glycosaminoglycan; conjugation; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. LÄS MER

  3. 7. Magnesium Chelatase: Insights into the first Step of Chlorophyll Biosynthesis

    Författare :Nick Sirijovski; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Electron microscopy; Proteobacteria; Mutants; Rhodobacter capsulatus; Tetrapyrrole; Plant biochemistry; Växtbiokemi; Biochemistry; Metabolism; Biokemi; metabolism; Proteins; enzymologi; enzymology; Proteiner; Chlorophyll biosynthesis; AAA proteins; Magnesium chelatase; Barley; ATPase;

    Sammanfattning : The enzyme magnesium chelatase inserts magnesium into protoporphyrin IX (Proto) to produce to magnesium protoporphyrin IX, the first unique intermediate of the chlorophyll biosynthetic pathway. Magnesium chelatase is composed of three distinct proteins termed I (molecular weight ~40 kDa), D (~70 kDa) and H (~140 kDa). LÄS MER

  4. 8. Studies of genes involved in regulating flowering time in Arabidopsis

    Författare :Maria Svensson; Högskolan i Skövde; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; flowering time; fold recognition; GA biosynthesis; promoter trapping; RNA-binding; T-DNA tagging; Biology; Biologi; Naturvetenskap; Natural sciences;

    Sammanfattning : Transition from a vegetative growth phase to flowering in plants occurs in response to both environmental conditions and endogenous signals. Identification of genes that are involved in regulating the time of flowering is of great importance in agri- and horticulture. LÄS MER

  5. 9. Polyamines are involved in the regulation of S phase and DNA synthesis

    Författare :Kersti Alm; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Djurfysiologi; Animal physiology; cell cycle regulation; p53; DNA strand breaks; replicon organization; topoisomerase II;

    Sammanfattning : Our research group has previously shown that treatment with the polyamine biosynthesis inhibitors a-difluoromethylornithine (DFMO) or amidinoindan-1-one 2´-amidinohydrazone (CGP 48664) inhibited S phase progression before any other cell cycle phase was affected. This study was undertaken to further investigate the role of polyamines in the regulation of S phase progression and DNA synthesis. LÄS MER

  7. 10. Biosynthesis of leukotriene B4 in hematological malignancies

    Författare :Gudmundur Runarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :LTB 4; 5-LO; cPLA 2; iPLA 2; AML; B-ALL; B-CLL;

    Sammanfattning : Leukotrienes (LT) are biologically active metabolites of the fatty acid arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA 2), this fatty acid can be converted to leukotrienes, lipoxins, prostaglandins or thromboxane. The conversion of AA to LTA 4 is catalyzed by five-lipoxygenase (5-LO). LÄS MER