Sökning: "DNA Probes"
Visar resultat 1 - 5 av 106 avhandlingar innehållade orden DNA Probes.
1. Development of benzoquinoquinoxaline derivatives as triplex-specific probes : Recognition of DNA structures at repeats sequences
Sammanfattning : Repeat sequences are associated with several human diseases, such as Friedreich’s ataxia, polycystic kidney disease and cancer. These sequences can form non-B-DNA structures, including triplex (H-DNA) DNA, and are associated with genomic instability and altered gene expression. LÄS MER
2. Padlock probes : Circularizing oligonucleotides for localized detection of DNA sequence variants
Sammanfattning : Present techniques for localized detection of DNA sequence variants have limitations due to problems with sensitivity, specificity, signal localization or ability to perform many analyses simultaneously.In this study a novel gene analytic reagent is presented - the padlock probe. LÄS MER
3. Strategies for de novo DNA sequencing
Sammanfattning : The development of improved sequencing technologies hasenabled the field of genomics to evolve. Handling andsequencing of large numbers of samples require an increasedlevel of automation in order to obtain high throughput andconsistent quality. LÄS MER
4. Fluorescence Probing of DNA Structures in Biology and Nanotechnology
Sammanfattning : Much has been learnt about DNA since its structure was discovered about half a century ago. Scientists everlasting urge to look beyond and deeper into the intricate machinery of life, has continuously pushed technology forward. LÄS MER
5. Fluorescent DNA Modifications for Use as Probes of Biological Structure and as Nanotechnological Functional Units
Sammanfattning : .... LÄS MER