Sökning: "DMC1"

Hittade 2 avhandlingar innehållade ordet DMC1.

1. 1. Identification of novel BRCA2-binding proteins that are essential for meiotic homologous recombination

   Författare :Jingjing Zhang; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; meiosis; DSB; cancer; BRCA2; MEILB2; BRME1; HR; RAD51; DMC1; DDR;

   Sammanfattning : Meiotic recombination is a molecular process in which the induction and repair of programmed DNA double-strand breaks (DSBs) creates genetic exchange between homologous chromosomes and thus increases genetic diversity and ensures chromosome segregation. Breast cancer susceptibility gene 2 (BRCA2) is a potent cancer suppressor and is required for DSB repair by homologous recombination (HR) in mitosis. LÄS MER

3. 2. Chromosome synapsis and recombination in yeast meiosis

   Författare :Hasanuzzaman Bhuiyan; Karin Schmekel; Harry Scherthan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; meiosis; recombination; synapsis; yeast; Molecular biology; Molekylärbiologi;

   Sammanfattning : Meiosis is a cell division process that produces haploid gametes from diploid cells. Several important meiotic events take place during prophase of meiosis I, most important being homologous chromosome pairing, meiotic recombination and formation of the synaptonemal complex (SC). LÄS MER