Visar resultat 1 - 5 av 2041 avhandlingar innehållade ordet DIFFERENTIATION.

  1. 1. Neural Stem Cell Differentiation and Migration

    Författare :Anna Erlandsson; Karin Forsberg-Nilsson; Bengt Westermark; Christer Betsholtz; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; CNS; stem cells; neuron; PDGF; SCF; differentiation; migration; ERK; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Neural stem cells are the precursors of neurons, astrocytes and oligodendrocytes. During neural development, the division of stem cells takes place close to the lumen of the neural tube, after which they migrate to their final positions within the central nervous system (CNS). LÄS MER

  2. 2. Molecular Mechanisms in Endothelial Cell Differentiation

    Författare :Emma Rennel; Pär Gerwins; Lena Claesson-Welsh; Ian Zachary; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; angiogenesis; FGF-2; VEGF-A; signal transduction; in vitro angiogenesis assay; immortalized brain endothelial cells; H-Ras; tetracycline-regulated gene expression; microarray; telomerase immortalized human microvascular endothelial cells; differentiation; Patologi; Pathology; Patologi;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. LÄS MER

  3. 3. Den sociala differentieringens retorik och gestaltning : Kritiska perspektiv på funktionalistisk förorts- och bostadsplanering i Stockholm från 1900-talets mitt

    Författare :Christian Björk; Hans Hayden; Helena Kåberg; Martin Rörby; Stockholms universitet; []
    Nyckelord :HUMANITIES; HUMANIORA; Swedish welfare state; Stockholm; Functionalism; Suburban planning; City planning; Urban Policy; Differentiation; Segregation; Spatial separation; Housing planning; Interior decoration; Upper middle-class; Private sphere; Public sphere; Gender coded rooms; Consumption; konstvetenskap; Art History;

    Sammanfattning : In this thesis, I analys suburb- and housing planning and interior decoration carried out primarily in Stockholm between the 1930s and the 1950s. Functionalism, the overall concept of the period, has perhaps been interpreted in terms of ideological concepts, interpreted as "democratic" and as a progressive dividing line between the past and the future. LÄS MER

  4. 4. Hypoxia and differentiation in human neuroblastoma cells

    Författare :Helén Nilsson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ontogeny; embryology human ; Utvecklingsbiologi; teratologi; embryologi människa ; teratology; cytogenetik; Development biology; cytogenetics; Genetik; Genetics; Medicin människa och djur ; HIF; Medicine human and vertebrates ; MYCN; Hypoxia; differentiation; Neuroblastoma;

    Sammanfattning : The childhood tumour neuroblastoma is derived from immature cells of the sympathetic nervous system, which have become arrested at different maturation stages. Neuroblastoma is a malignancy with a high degree of heterogeneity, and there is a correlation between a poor differentiation status and a more aggressive phenotype. LÄS MER

  5. 5. Device Bonding and Antibody Binding: Developments for On-Chip Differentiation of Induced Pluripotent Stem Cells into Hepatocytes

    Författare :Philip Dalsbecker; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Microfluidics; liver-on-a-chip; organ-on-chip; PDMS; oxygen plasma; immunofluorescence; fluorescence microscopy; hepatocytes; iPSC; induced pluripotent stem cells; differentiation; on-chip differentiation; definitive endoderm;

    Sammanfattning : Abstract This thesis describes the bonding optimization of a liver-on-a-chip microfluidic device for evaluation of cultured induced pluripotent stem cell (iPSC)-derived definitive endoderm (DE) cells during their targeted differentiation into mature hepatocytes. Furthermore, it describes the optimization of a number of antibody assays for use during said differentiation, for the purpose of studying the cellular phenotype. LÄS MER