Sökning: "D.discoideum"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet D.discoideum.
1. Making Sense of Antisense
Sammanfattning : RNA is a highly versatile molecule with functions that span from being a messenger in the transfer from DNA to protein, a catalytic molecule important for key processes in the cell to a regulator of gene expression. The post-genomic era and the use of new techniques to sequence RNAs have dramatically increased the number of regulatory RNAs during the last decade. LÄS MER
2. A small amoeba at the crossroads of the big RNAi world : MicroRNA biogenesis and Argonaute function in Dictyostelium discoideum
Sammanfattning : Small non-coding RNA (ncRNA) mediated gene silencing, known as RNAi, is a key regulatory mechanism of gene expression in eukaryotes. MicroRNAs (miRNA), one major type of small ncRNAs, are about 21nt long and bound by Argonaute proteins. LÄS MER
3. All Roads Lead to the Non-Coding RNome : Evolution of Multicellularity and Host Response to Bacterial Infection
Sammanfattning : The ability to control gene expression is fundamental for all living organisms. Therefore, a large variety of regulatory mechanisms exist in each cell which are essential for e.g. developmental processes and to quickly adapt to different cellular stresses such as infection. LÄS MER
4. Ancient roles of non-coding RNAs in eukaryotic evolution : contributions from social amoebae and other protists
Sammanfattning : RNAs not coding for proteins, non-coding RNAs (ncRNAs) have many important roles in all kingdoms of life. Especially in eukaryotes, the regulatory functions of ncRNAs have been suggested as a major force in the evolution of complex traits. LÄS MER
5. Function and Evolution of Small Regulatory RNAs and their Associated Proteins : A Journey from Genome to Proteome
Sammanfattning : Organisms throughout the tree of life have evolved distinct ways to regulate gene expression. Some of these processes involve non-coding RNAs (ncRNAs), which are not translated but functional nonetheless. These ncRNAs are of utmost importance, with dysregulation of some causing severe developmental effects or even being lethal. LÄS MER