Sökning: "D-amino acids"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden D-amino acids.

  1. 1. Molecular mechanisms and biological consequences of the production of non-canonical D-amino acids in bacteria

    Författare :Alena Aliashkevich; Felipe Cava; Fredrik Almqvist; Andrew J Roe; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; D-amino acids; LD-transpeptidase;

    Sammanfattning : Most bacteria possess a vital net-like macromolecule – peptidoglycan (PG). PG encases bacteria around the cytoplasmic membrane to withstand the high internal turgor pressure and thereby protect the cell from bursting. In addition, PG is a major morphological determinant of bacteria being both required and sufficient to maintain cell shape. LÄS MER

  3. 2. Uncovering novel cell wall chemistries in gram negative bacteria : from development or dedicated peptidoglycan chemometric tools to functional genomics

    Författare :Akbar Espaillat; Felipe Cava; Sun Nyunt Wai; Waldemar Vollmer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; peptidoglycan variations; D-amino acids; molekylärbiologi; Molecular Biology;

    Sammanfattning : Bacteria are surrounded by an external cell wall whose main component is a polymeric net-like structure called the peptidoglycan (PG) or murein sacculus. PG plays crucial roles in bacterial physiology (eg morphogenesis, growth fitness and regulation of innate immunity). LÄS MER

  4. 3. On plant responses to D-amino acids : features of growth, root behaviour and selection for plant transformation

    Författare :Oskar Forsum; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Amino acids have been regarded as potential plant nitrogen sources for more than a century. Some amino acids have been shown to support growth while others have growth-retarding effects. The D-isomers with notably adverse effects on plants’ growth and development include D-serine and D-alanine. LÄS MER

  5. 4. Exotic Ribosomal Enzymology

    Författare :Josefine Liljeruhm; Anthony C. Forster; Christophe Danelon; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; rRNA modification; Methyltransferase; RlmM; RlmJ; D-amino acid; Unnatural amino acid; Chromoprotein; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : This thesis clarifies intriguing enzymology of the ribosome, the multiRNA/multiprotein complex that catalyzes protein synthesis (translation). The large ribosomal RNAs (23S and 16S rRNAs in E. coli) are post-transcriptionally modified by many specific modification enzymes, yet the functions of the modifications remain enigmatic. LÄS MER

  7. 5. Enzymatic and Immunological Detection Principles for Environmental and Biological Applications

    Författare :Elisabeth Burestedt; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; interleukin-8; D-ammino acids; carbon paste; flow immunoassays; Amperometric biosensors; phenols; Analytisk kemi;

    Sammanfattning : The aim of the thesis was to develop new analytical detection principles based on enzymatic and immunological reactions for sensitive, selective, cost-effective and high sample through-put detection devices. The thesis presents the basic elements and reaction paths necessary for the construction and development of enzyme based amperometric biosensors and immunoassays. LÄS MER