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  1. 1. Modulation of Autoimmunity by Linomide treatment or interference with costimulation

    Författare :Annamaria C Tellander; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; collagen-induced arthritis; CD28; CD40; antigen presenting cells; Linomide; thymocytes; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : Linomide is a potent immunomodulator that has been shown to inhibit autoimmunity in several animal models of autoimmune disease. We have approached the cellular and molecular mechanism of Linomide by investigating its effect on thymocyte development and its capacity to modulate the expression of activation markers on antigen presenting cells (APCs). LÄS MER