Sökning: "Cyclooxygenase"

Visar resultat 16 - 20 av 116 avhandlingar innehållade ordet Cyclooxygenase.

  1. 16. Endocannabinoid metabolism : the impact of inflammatory factors and pharmacological inhibitors

    Författare :Jessica Karlsson; Christopher Fowler; Stig Jacobsson; Jürg Gertsch; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endocannabinoid; anandamide; 2-AG; fatty acid amide hydrolase; cyclooxygenase-2; prostate cancer; catabolism; inflammation; inflammatory factors;

    Sammanfattning : The endocannabinoid (eCB) system is an endogenous signaling system consisting of ligands (referred to as endocannabinoids, eCBs), receptors and metabolic enzymes. The eCB system is involved in homeostatic control of a variety of biological functions such as neuronal signaling, mood, appetite and pathological conditions such as pain, inflammation and tumour progression. LÄS MER

  3. 17. Bioassay Development for Identification of Cyclooxygenase-2 Inhibitors of Natural Origin

    Författare :Therese Ringbom; Angelika Vollmar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; Farmakognosi; Pharmacognosy; Farmakognosi; Pharmacognosy; farmakognosi;

    Sammanfattning : To examine cyclooxygenase-2 (COX-2) inhibitory effects of natural compounds and structurally related compounds, a radiochemical assay for measuring inhibition of COX-2 and COX-1 catalysed prostaglandin biosynthesis was optimised. That process resulted in the development of a reliable assay for finding COX-2 inhibitors in plants, and for investigating plant constituents pertaining to the inhibition of COX-2 and COX-1. LÄS MER

  4. 18. Studies on the Effects of Plant and Food Constituents on Cyclooxygenase-2 : Aspects in Inflammation and Cancer

    Författare :Ulrika Huss; Pia Wuorela; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; Farmakognosi; Pharmacognosy; Farmakognosi;

    Sammanfattning : In inflammatory events, the cyclooxygenase-2 enzyme (COX-2) catalyses prostaglandin biosynthesis. This is a process, which could possibly be affected by natural compounds including those abundant in food. Two systems have been established to enable investigations of the effects of natural compounds on COX-2. LÄS MER

  5. 19. Studies of duodenal protective mechanisms : effects of hydrochloric acid, and of cyclooxygenase and nitric oxide synthase inhibition

    Författare :Manaf Sababi; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 20. Separation and bioassay in identification of cyclooxygenase inhibitors from plants, with emphasis on flavonoids

    Författare :Ylva Noreen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER