Sökning: "Cyclin-Dependent Kinase Inhibitor p21"

Hittade 2 avhandlingar innehållade orden Cyclin-Dependent Kinase Inhibitor p21.

  1. 1. Intoxication of mammalian cells by the cytolethal distending toxin of Haemophilus ducreyi : a novel mechanism of action

    Författare :Ximena Cortes Bratti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The cytolethal distending toxins (CDTs) are a newly described family of bacterial protein toxins with a novel mechanism of action: DNA damage. Haemophilus ducreyi produces a cytotoxin that belongs to this family. This bacterium causes chancroid, a sexually transmitted disease, characterised by mucocutaneous, slowly healing genital ulcers. LÄS MER

  2. 2. Effects of interferon on cellular proliferation and apoptosis

    Författare :Olle Sangfelt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :interferon; malignancy; apoptosis; cell cycle;

    Sammanfattning : Interferon (IFN) therapy is today a well-established treatment in many diseases, including various malignancies. How IFN exerts antitumor activity is not known, but several mechanisms have been suggested. LÄS MER