Sökning: "CpxA"

Hittade 2 avhandlingar innehållade ordet CpxA.

1. 1. Controlling virulence in Yersinia pseudotuberculosis through accumulation of phosphorylated CpxR

   Författare :Edvin Thanikkal; Matthew Francis; Andrew Darwin; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Y. pseudotuberculosis; CpxA; CpxR; invasin; RovA; RovM; T3SS; virulence; transcriptional regulation; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

   Sammanfattning : Like many Gram-negative bacteria, the food-borne pathogen Yersinia pseudotuberculosis harbours different regulatory mechanisms to maintain an intact bacterial envelope especially during exposure to extracytoplasmic stress (ECS). The CpxA-CpxR two component regulatory system is one such ECS-responsive regulatory mechanism. LÄS MER

3. 2. Exploring the Interplay of Lipids and Membrane Proteins

   Författare :Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; Biochemistry; biokemi;

   Sammanfattning : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. LÄS MER