Sökning: "Controlled-release"

Visar resultat 16 - 20 av 56 avhandlingar innehållade ordet Controlled-release.

  1. 16. Drug Eluting Hydrogels : Design, Synthesis and Evaluation

    Författare :Lage Ahrenstedt; Deon Bezuidenhout; Michael Malkoch; University of Cape Town; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drug delivery; PEGylation; Rapamycin; Dexamethasone; Controlled release; Hydrogels; Slow release;

    Sammanfattning : Hydrogels have successfully proved themselves useful for drug delivery applications and several delivery routes have been developed over the years. The particular interest in this work was to design, synthesise and evaluate in situ forming drug eluting hydrogels, which have the potential to ameliorate the healing of cardiovascular diseases. LÄS MER

  3. 17. Microgels as drug delivery vehicles : loading and release of amphiphilic drugs

    Författare :Yassir Al-Tikriti; Per Hansson; Magnus Bergström; Matthew Libera; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microgel; amphiphilic drug; phase separation; micropipette; Raman microscopy; controlled release; drug delivery; SAXS; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : Polyelectrolyte microgels are used as delivery vehicles for amphiphilic drugs in, e.g., treatments of liver cancer by a method called trans-arterial chemoembolization. LÄS MER

  4. 18. Modelling of Drug Release from Reservoir and Matrix Formulations - Multiple Unit Dosage Forms and Swelling and Dissolving Matrix Systems

    Författare :Per Borgquist; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; swelling; XEDS; Chemical technology and engineering; Kemiteknik och kemisk teknologi; Polymer technology; biopolymers; Polymerteknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik; simulation; single pellet; single-unit release; SEM; reservoir system; poly ethylene oxide ; film-coated; matrix; mathematical model; diffusion; pellet shape; controlled release; polymer dissolution; modelling; ethyl cellulose; Coating; multiple-unit release;

    Sammanfattning : In this work, mathematical models have been developed describing drug release from film-coated reservoir systems as well as drug release and polymer dissolution from swelling and dissolving polymer tablets. The model derivation of both systems is based on a mechanistic approach. The model describing drug release from reservoir systems, i.e. LÄS MER

  5. 19. Prolonged Drug Release from Gels, using Catanionic Mixtures

    Författare :Tobias Bramer; Katarina Edsman; Per Hansson; Stefan Ulvenlund; Uppsala universitet; []
    Nyckelord :Pharmaceutics; gel; catanionic; vesicle; micelle; controlled release; diffusion; surfactant; drug delivery; Galenisk farmaci;

    Sammanfattning : The use of catanionic drug-surfactant mixtures was proven to be an efficient novel method of obtaining prolonged drug release from gels. It was shown that various commonly used drug compounds are able to form catanionic mixtures together with oppositely charged surfactants. LÄS MER

  7. 20. Bacteria-responsive materials for drug delivery

    Författare :Marina Craig; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; triggered release; multilayer; controlled release; Layer-by-layer; nanofilm; infection; enzymatic degradation;

    Sammanfattning : The number of diabetics, obese individuals and other patients carrying other lifestyle diseasesis increasing worldwide. At the same time the population is ageing. These patients all sufferfrom poor blood circulation, which often gives rise to non-healing, or chronic, wounds. Thus,the number of chronic wounds is also increasing at a fast pace. LÄS MER