Sökning: "Controlled-release"

Visar resultat 11 - 15 av 56 avhandlingar innehållade ordet Controlled-release.

  1. 11. Harnessing Mesoporous Spheres - transport studies and biotechnological applications

    Författare :Jovice Boon Sing Ng; Lennart Bergström; Frank Caruso; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mesoporous; spheres; particles; CLSM; TEM; controlled-release; molecular transport; lipid membrane; enzyme; intraparticle; lipase; solid support; Inorganic chemistry; Oorganisk kemi; materialvetenskap; Materials Science;

    Sammanfattning : Applications in controlled release and delivery calls for a good understanding of molecular transport within the carrier material and the dominating release mechanisms. It is clear that a better understanding of hindered transport and diffusion of guest molecules is important when developing new porous materials, e.g. LÄS MER

  3. 12. Controlled release gel formulations and preclinical screening of drug candidates

    Författare :Tofeeq Ur-Rehman; Gerhard Gröbner; Mikael Elofsson; Åsa Gylfe; Martin Malmsten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; poloxamer; drug delivery; micellization; DMSO; calorimetry; NMR. in situ gelation; chitosan; preclinical pharmacokinetics; type III secretion inhibitors; Physical chemistry; Fysikalisk kemi; Pharmaceutics; galenisk farmaci;

    Sammanfattning : Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermo-reversible poloxamer gels, which are suitable for novel drug delivery applications. LÄS MER

  4. 13. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

    Författare :Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Sammanfattning : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. LÄS MER

  5. 14. Mass Transport through Phase Separated Films - Effects of Ethyl Cellulose Molecular Weight on Cellulose Derivative Blends for Pharmaceutical Coatings

    Författare :Helene Andersson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coating; Ethyl cellulose; Diffusion; Mass transport; Solvent evaporation; Molecular weight; Phase separation; Film; Hydroxypropyl cellulose; Polymer blend; Cellulose derivatives; Controlled release;

    Sammanfattning : Polymer blends are utilized for a variety of applications, not least in pharmaceutical coatings for controlled release of drugs. For instance, blends of ethyl cellulose (EC) and the water-soluble hydroxypropyl cellulose (HPC) can be used to coat drug pellets for oral extendedrelease formulations. LÄS MER

  7. 15. Experimental Design and Evaluation of Biocide Release from Microcapsules

    Författare :Jonatan Bergek; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; microsphere; microscopic and macroscopic porosity; controlled release; internal phase separation method; Microcapsule; biocide; polyelectrolyte multilayer;

    Sammanfattning : To protect a painted house façade from mold or algae, anti-growth agents are usually mixed in the paint. The protection of paint systems used in the past relied on heavy metals for protection and are banned today due to their negative impact on the environment. LÄS MER