Sökning: "Conjugation"
Visar resultat 11 - 15 av 212 avhandlingar innehållade ordet Conjugation.
11. Exploring molecular interactions between polypeptide conjugates and protein targets : Manipulating affinity by chemical modifications
Sammanfattning : In this thesis molecular interactions between polypeptide conjugates and protein targets were investigated. Polypeptides were derivatized with small organic molecules, peptides and oligonucleotides. New strategies were developed with the aim to increase affinities for proteins of biological interest. LÄS MER
12. The role of wastewater in surveillance and emergence of antibiotic resistant bacteria
Sammanfattning : As antibiotic resistance spreads among bacterial pathogens, it reduces treatment options and increases treatment failures of infectious diseases. Strategies employed to reduce this spread or adapt to its consequences need to be based on reliable surveillance data which is lacking in many countries, often due to limited resources. LÄS MER
13. On the linearization of non-Archimedean holomorphic functions near an indifferent fixed point
Sammanfattning : We consider the problem of local linearization of power series defined over complete valued fields. The complex field case has been studied since the end of the nineteenth century, and renders a delicate number theoretical problem of small divisors related to diophantine approximation. LÄS MER
14. Toxicometabolomics and biotransformation product screening in single zebrafish embryos
Sammanfattning : Over the last decade environmental agencies worldwide have escalated their work to phase out animal testing for the purposes of chemical regulation. Meanwhile the number of commercially available chemicals and the requirements for hazard assessments have both increased, creating a large need for substitution of traditional in vivo assays with in vitro tests. LÄS MER
15. Organic Heavy Group 14 Element Compounds : A Study of Their Chemical Bonding Properties Directed Towards Applications as Molecular Wires and in Synthesis
Sammanfattning : The research described herein includes synthesis, spectroscopy, and quantum chemical calculations with focus on the characteristic properties of compounds with bonds between carbon and the heavier Group 14 elements.The chapters based on the first four papers concern σ- and σ/π-conjugated compounds, although the focus of the first paper is on ring strain of bicyclo[1. LÄS MER