Sökning: "Complement regulation"

Visar resultat 11 - 15 av 101 avhandlingar innehållade orden Complement regulation.

1. 11. Synaptic elimination and the complement system in Alzhaimer's disease

   Författare :Jonny Daborg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synapse; Alzheimer s disease; Genetics; CSF; Complement; RAGE;

   Sammanfattning : The mechanisms behind Alzheimer’s disease (AD) are largely unknown. The disease is to a large extent hereditary, and the best pathophysiological correlate to the severity of the symptoms is loss of synapses. LÄS MER

3. 12. Emotion regulation and chronic illness : The roles of acceptance, mindfulness and compassion in physical and mental health

   Författare :Ines Trindade; Cláudia Rute Carlos Ferreira; José Augusto da Veiga Pinto Gouveia; Portugal Coimbra Faculdade de Psicologia e de Ciências da Educação da Universidade de Coimbra; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic illness; behavioural medicine; inflammatory bowel disease; cancer; chronic illness-specific measures; mental health; physical health; emotion regulation; acceptance and commitment therapy; mindfulness; compassion-focused therapy; MIND programme; doença crónica; medicina comportamental; doença inflamatória intestinal; cancro; medidas específicas para a doença crónica; saúde mental; saúde física; regulação emocional; terapia de aceitação e compromisso; mindfulness; terapia focada na compaixão; programa MIND;

   Sammanfattning : Introduction: Chronic illness is an increasingly predominant problem among the world population which vastly impacts on physical and mental health, quality of life and social functioning. Although chronic illnesses merit a long-term and complex response which would be ideally delivered by a multidisciplinary team of health professionals, most of the current healthcare for chronic illnesses still focus on acute episodes of illness. LÄS MER

4. 13. Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies

   Författare :Zhoujie Ding; Birgitta Heyman; Eva Severinson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgE; IgM; IgG3; antibody responses; T-cell responses; antigen transportation; antigen presentation; complement; complement receptors 1 and 2; Immunologi; Immunology;

   Sammanfattning : Antibodies can enhance or suppress the immune responses against their specific antigens. This phenomenon is known as antibody-mediated feedback regulation. We have studied the mechanisms underlying IgE-, IgM-, and IgG3-mediated enhancement of immune responses in mouse models using intravenous immunization. LÄS MER

5. 14. Modern roles for an ancient system. Intracellular Complement in the regulation of β cell function

   Författare :Ewelina Golec; Malmö Proteinkemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; Diabetes mellitus; Insulin secretion; CD59; C3; Isoforms; SNARE proteins;

   Sammanfattning : Type 2 diabetes (T2D) is characterised by defective insulin exocytosis from the pancreatic β cells, accompanied by insulin resistance. Reduced β cells mass is often seen in T2D individuals, caused by enhanced β cells apoptosis. It is now understood that several components drive β cells dysfunction and apoptosis. LÄS MER

7. 15. IgG3 Complements IgM in the Complement-Mediated Regulation of Immune Responses

   Författare :Lu Zhang; Birgitta Heyman; Jenny Hallgren; Frida Henningsson; Kristina Lejon; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgG3; IgM; marginal zone B cells; follicular dendritic cells; complement receptors 1 and 2; C1q; C3; antigen transport; Immunologi; Immunology;

   Sammanfattning : An intact complement system is essential for the initiation of a normal antibody response. Antibodies can regulate their own production against the antigens that they are specific for. Both IgG3 and IgM are able to enhance the antibody response via complement. LÄS MER