Sökning: "Complement C3a"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden Complement C3a.

  1. 1. The role of the complement system in basal and ischemia-induced neurogenesis

    Författare :Yalda Rahpeymai Bogestål; Göteborgs universitet; []
    Nyckelord :complement; C3a; C5a; adult neurogenesis; neural stem cells; brain ischemia;

    Sammanfattning : .... LÄS MER

  3. 2. Novel Endogenous Antimicrobial Peptides

    Författare :Emma Nordahl; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D5; HK; C3a; HMWK; complement; heparin-binding; antibacterial; Antimicrbial peptide; AMP;

    Sammanfattning : Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. LÄS MER

  4. 3. Complement Activation Triggered by Biomaterial Surfaces : Mechanisms and Regulation

    Författare :Jonas Andersson; Bo Nilsson; Hans Elwing; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Biomaterials; Biocompatibility; Blood; Complement; Immunologi; Immunology; Immunologi; klinisk immunologi; Clinical Immunology;

    Sammanfattning : Today there are a vast number of medical devices in temporary or permanent contact with human tissues. Blood-biomaterial contact is known to trigger the complement system and results in generation of fluid phase anaphylatoxins C3a and C5a, and surface-bound C3b and iC3b. LÄS MER

  5. 4. Crosstalk Between Activated Platelets and the Complement System

    Författare :Osama A. Hamad; Bo Nilsson; Kristina Ekdahl-Nilsson; Lennart Truedsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; activated platelets; TRAP; chondroitin sulfate; C1q; factor H; C4BP; C3; Compstatin; complement; platelet-leukocyte complexes; platelet microparticles; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER

  7. 5. Inflammation and Cell Profileration Following Perinatal Brain Injury

    Författare :Katarina Järlestedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypoxia-ischemia; immature brain; reactive gliosis; complement system; C3a; fear conditioning; lipopolysaccharide; inflammation;

    Sammanfattning : Inflammation plays an important role in cerebral ischemic injury in the immature brain. The aim of the thesis was to investigate (1) the role of astrocyte activation and reactive gliosis in neonatal hypoxic-ischemic (HI) brain injury, (2) the role of complement derived peptide C3a in neonatal HI brain injury, (3) the effect of neonatal HI brain injury on fear learning and behaviour, (4) the effects of lipopolysaccharide (LPS) induced systemic inflammation on cell proliferation in the developing brain. LÄS MER