Sökning: "Comet assay"
Visar resultat 16 - 20 av 27 avhandlingar innehållade orden Comet assay.
16. Single-molecule Detection in situ
Sammanfattning : The human body contains a variety of different cell types that share a common genome, but differ in how they use the information encoded therein. Variation in molecular content exists even at the level of individual cells, and to provide deeper insight into complex cellular processes methods that permit analysis of each cell on its own are needed. LÄS MER
17. Particularly harmful particles? A study of airborne particles with a focus on genotoxicity and oxidative stress
Sammanfattning : Today it is well established that particulate matter (PM) cause a wide range of health effects. The underlying mechanisms likely include inflammation, oxidative stress and genotoxicity. There is however a lack of knowledge regarding how particles from different sources contribute to these effects. LÄS MER
18. Toxicity of metal containing micro- and nanoparticles : studies from an inhalation perspective
Sammanfattning : Particles in urban environments have for a long time been associated with different health problems and diseases, such as worsening of asthma and chronic obstructive pulmonary disease as well as cancer and cardiovascular diseases. In addition, metal containing particles present in occupational settings and industries, particularly particles produced during welding, have been linked to several adverse health effects. LÄS MER
19. Health Promoting Effects of Bioactive Peptides in Milk - Studies on Cultured Normal Cells and Cancer Cells
Sammanfattning : This thesis concerns the bioactive peptides lactoferricin and ubiquitin and findings suggesting that they have ability to modify the risk of cancer. It is known that components in bovine milk may improve human health and modify the risk of diseases. Examples of such compounds are bioactive peptides, i.e. LÄS MER
20. Mechanisms behind Cadmium-Induced Teratogenicity
Sammanfattning : Heavy metals polluting our environment cause concern for developing organisms. Among them, cadmium with extremely slow elimination from the body, causes lower birth weight in humans but has not been classify as a human teratogen. Studies in different laboratory animals have shown that cadmium indeed is a potent teratogen. LÄS MER