Sökning: "Colorectal cancer"

Visar resultat 11 - 15 av 263 avhandlingar innehållade orden Colorectal cancer.

  1. 11. Prostanoids and colorectal cancer

    Författare :Annika Gustafsson Asting; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer prostanoid receptors cyclooxygenase PGE2 transcription factors;

    Sammanfattning : Tumor disease is a main cause of death in Western countries and a most common malignancy is colorectal cancer (CRC). Growing tumors are dependent on interactions among several different cells as well as signaling pathways. LÄS MER

  2. 12. Targeting allelic loss in colorectal cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Verónica Rendo; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; gene editing; loss of heterozygosity; targeted therapy; whole genome sequencing;

    Sammanfattning : Targeted cancer therapy exploits molecular differences between tumor and normal cells to selectively kill cancer cells. Whereas targeting of activated oncogenes has proved clinically useful, few current therapies exploit loss-of-function mutations in tumor suppressor genes or in the genome at large. LÄS MER

  3. 13. Diagnosing colorectal cancer in primary care the value of symptoms, faecal immunochemical tests, faecal calprotectin and anaemia

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Cecilia Högberg; Umeå universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; faecal immunochemical tests; faecal calprotectin; anaemia; symptomatic patients; rectal bleeding; primary care;

    Sammanfattning : Background: Colorectal cancer (CRC) is the third most common cancer in men and the second most common in women worldwide. Adenomas can be precursors to CRC, and inflammatory bowel disease (IBD) can present with the same symptoms as CRC. The majority of patients with CRC initially consult primary care. LÄS MER

  4. 14. Metabolic Risk Factors and Molecular Subtypes of Colorectal Cancer

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Robin Myte; Umeå universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; risk factors; metabolic syndrome; one-carbon metabolism; molecular subtypes; KRAS; BRAF; MSI; molecular pathological epidemiology; Cancer Epidemiology; cancerepidemiologi;

    Sammanfattning : Background: Colorectal cancer (CRC) is a heterogeneous disease developing from distinct pathways, resulting in tumor subtypes with large differences in clinical and molecular characteristics. Molecular characteristics are increasingly being used clinically to guide therapy. LÄS MER

  5. 15. Biomarkers of one-carbon metabolism in colorectal cancer risk

    Detta är en avhandling från Umeå : Umeå University

    Författare :Björn Gylling; Umeå universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; one-carbon metabolism; biomarkers; folate; epidemiology; Cancer Epidemiology; cancerepidemiologi;

    Sammanfattning : One-carbon metabolism, a network of enzymatic reactions involving the transfer of methyl groups, depends on B-vitamins as cofactors, folate as a methyl group carrier, and amino acids, betaine, and choline as methyl group donors. One-carbon metabolism influences many processes in cancer initiation and development such as DNA synthesis, genome stability, and histone and epigenetic methylation. LÄS MER