Sökning: "Colonic anastomotic healing"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Colonic anastomotic healing.

  1. 1. Experimental Colonic Obstruction and Anastomotic Healing

    Författare :Martin Rehn; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstruction; anastomosis; colon; wound healing; matrix metalloproteinases; collagen; MMP inhibition;

    Sammanfattning : Colorectal cancer is one of the most common malignant diseases world-wide. Most patients can be diagnosed, staged and treated by surgery in an elective setting. However, about one fifth of the patients will have an emergency presentation and in most cases due to malignant obstruction of the left colon. LÄS MER

  3. 2. Inflammation and neutrophil recruitment in healing of colonic anastomosis

    Författare :Peter Månsson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; experimetnal; anastomotic healing; Inflammation; neutrophil redruitment; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Wound healing is a multistep process with an initial inflammatory response, followed by synthesis of extracellular matrix components and finalized by a repair phase. One main goal was to determine the impact and adhesive mechanisms of neutrophil recruitment in anastomotic healing in the colon. LÄS MER

  4. 3. Colonic pouch anastomosis after rectal excision for cancer

    Författare :Olof Hallböök; Neil J. M. Mortensen; Linköpings universitet; []
    Nyckelord :Total mesorectal excision; low anterior resection; colonic pouch; coloanal anastomosis; neorectum; quality of life; laser-Doppler flowmetry; gut peptides; anorectal physiology; MEDICINE; MEDICIN;

    Sammanfattning : Anastomoses at the level of the pelvic floor will become increasingly more common in rectal cancer surgery when total mesorectal excision is used as a standard procedure to obtain local mdicality. A consequence of such low anastomoses is increased risk of healing disturbances and poor distal bowel function, The aim of this thesis was to focus on reconstruction after total mesorectal excision. LÄS MER

  5. 4. PREVENTION OF POSTSURGICAL ABDOMINAL ADHESIONS BY POLYPEPTIDES

    Författare :Laszlo Nehéz; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Surgery; orthopaedics; poly-L-glutamate; anastomotic healing; peritoneum; adhesion; prevention; poly-L-lysine; traumatologi; Kirurgi; ortopedi; polypeptides; surgery;

    Sammanfattning : Peritoneal adhesions develop after almost all abdominal surgical interventions and represent an important cause of postoperative intestinal obstruction, abdominal discomfort and infertility. Postoperative adhesions can potentially be reduced by using different antiadhesive agents. LÄS MER

  7. 5. Systemic and Local Inflammatory Mediator Response to Major Surgery

    Författare :Ingvar Syk; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Surgery; traumatologi; ortopedi; Kirurgi; traumatology;

    Sammanfattning : Cell-signalling via cytokines modulates the local response to surgical trauma, directs the immunologic response and initiates the healing process. Surgical trauma induces a systemic cytokine response and a down-regulation of the antigen presentation capacity of monocytes (HLA-DR expression), which is associated with a poor prognosis if pronounced. LÄS MER