Sökning: "Cohort study"

Visar resultat 6 - 10 av 2508 avhandlingar innehållade orden Cohort study.

  1. 6. On the aetiology of ALS : a comprehensive genetic study

    Författare :Caroline Ingre; Peter M Andersen; Rayomand Press; Siddharthan Chandran; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; risk factor; VAPB; SOD1; amyotrophic lateral sclerosis; ATXN2; SMN1; SMN2; PFN1; 50 bp deletion in SOD1 promotor; population-specific genetic variations; Neurology; neurologi;

    Sammanfattning : Introduction: Amyotrophic lateral sclerosis (ALS) is a deadly, progressive neuromuscular disease that affects individuals all over the world. About 10% of the patients have a familial predisposition (FALS) while the remainder of cases are isolated or sporadic (SALS) and of unknown cause. LÄS MER

  3. 7. Comorbidity and vascular risk factors  associated with idiopathic normal pressure hydrocephalus : the INPH-CRasH Study

    Författare :Hanna Israelsson Larsen; Jan Malm; Anders Eklund; Norman Relkin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hydrocephalus; normal pressure; vascular disease; vascular risk factors; elderly; depression; case control study; epidemiology; dementia; vascular dementia; small vessel disease; cerebrovascular disease; transient ischemic attack; Neurology; neurologi;

    Sammanfattning : Idiopathic normal pressure hydrocephalus (INPH) is a dementia treatable by insertion of a cerebrospinal fluid shunt. It has been suggested that INPH has similar pathophysiological mechanisms as cerebrovascular disease, but the vascular risk factor (VRF) profile of INPH patients has not been assessed using a modern epidemiological approach. LÄS MER

  4. 8. Dupuytren´s Contracture : Features and Consequences

    Författare :Stephan Wilbrand; Lars Dahlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Dupuytren´s contracture; epidemiology; outcome study; cohort; prognostic factors; immunohistochemistry; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Dupuytren's contracture (DC) is a fibromatous disease of the palmar fascia of unknown etiology. The present study was undertaken in order to assess pathophysiological mechanisms and consequences. In a cohort study of 2,375 patients operated for DC at the Department of Hand Surgery, Uppsala there was a male: female ratio of 5.9:1. LÄS MER

  5. 9. Suicide in Russia : A macro-sociological study

    Författare :Tanya Jukkala; Ilkka Henrik Mäkinen; Vessela Misheva; Paavo Bergman; Steven Stack; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Suicide; Russia; historical development; time-series analysis; age-period-cohort analysis; Émile Durkheim; Niklas Luhmann;

    Sammanfattning : This work constitutes a macro-sociological study of suicide. The empirical focus is on suicide mortality in Russia, which is among the highest in the world and has, moreover, developed in a dramatic manner over the second half of the 20th century. LÄS MER

  7. 10. Lumbar spinal stenosis : Body mass index and the patient's perspective

    Författare :Björn Knutsson; Karl Michaëlsson; Bengt Sandén; Göran Sjödén; Paul Gerdhem; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antonovsky; back pain; BMI; body mass index; Bygghalsan; cohort study; coping; EQ-5D; excess weight; leg pain; LSS; lumbar spinal stenosis; obesity; ODI Oswestry disability index; overweight; patient-centered; patient-physician relationship; patient-perspective; patient-related-outcome-measure; PROMs; qualitative study; spinal stenosis; salutogenesis; salutogenic; sciatica; spine surgery; suffering; Swedish spine register; Swespine; VAS; weight loss; weight change; Orthopaedics; Ortopedi;

    Sammanfattning : During recent decades, lumbar spinal stenosis (LSS) has become the most common indication for spine surgery, a change that coincides with a higher worldwide prevalence of overweight and obesity. Thus, surgical treatment of LSS in the overweight and obese population is common and increasing in scope. LÄS MER