Sökning: "Coagulation system"

Visar resultat 1 - 5 av 134 avhandlingar innehållade orden Coagulation system.

  1. 1. Streptococcal virulence and the coagulation system

    Författare :Kristofer Wollein Waldetoft; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococci; virulence; coagulation; intrinsic pathway; evolution;

    Sammanfattning : This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are produced in different growth phases. LÄS MER

  3. 2. The Plasma Contact System : New Functional Insights from a Hemostatic and Thrombotic Perspective

    Författare :Jennie Bäck; Bo Nilsson; Kristina Nilsson Ekdahl; Ulla Hedner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Contact activation; factor XII; platelets; coagulation; antithrombin; C1 inhibitor; hemostasis; biomarkers; vascular disease.; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : The physiological role of the plasma contact system still remains a partial enigma. The aim of the presented work was to expand our understanding of the plasma contact system, focusing on its physiological activation and function, principally from a hemostatic perspective. It also explored contact system activation under pathological conditions. LÄS MER

  4. 3. Novel Aspects of the Coagulation System in Host Defence

    Författare :Praveen Papareddy; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Host defence peptides; Coagulation system; Sepsis; Thrombin; TFPI-1; TFPI-2; HCII;

    Sammanfattning : Bacterial infections are a major global threat to public health and sepsis is a major cause of morbidity and mortality. Sepsis incidence is rising, with supportive treatments and antibiotics being the main treatment possibilities. LÄS MER

  5. 4. Protamine, Platelet Function and Coagulation in Cardiac Surgery

    Författare :Mattias Törnudd; Sören Berg; John-Peder Escobar Kvitting; Sofia Ramström; Joakim Alfredsson; Ulf Schött; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiopulmonary bypass; Protamine; Platelet function; Coagulation;

    Sammanfattning : Bleeding is a serious and common complication in cardiac surgery. Complicated surgery together with alterations in hemostatic conditions from the use of cardiopulmonary bypass (CPB), presents challenges in how to preserve hemostasis in the patient.   CPB is thought to affect platelet function and coagulation in many ways. LÄS MER

  7. 5. Progressive Traumatic Intracerebral Contusions - Studies of the correlation to the biochemical environment and the coagulation system

    Författare :Martin Engström; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anestesiologi; intensivvård; Contusion; Anaesthesiology; intensive care; TBI; ROTEG; Thromboelastography; Coagulation; Traumatic Brain Injury; Microdialysis;

    Sammanfattning : [abstract missing].... LÄS MER