Sökning: "Clinical trial"
Visar resultat 1 - 5 av 997 avhandlingar innehållade orden Clinical trial.
1. The future of clinical trials for Alzheimer's disease. A blood-based biomarker perspective
Sammanfattning : Objectives: The primary objective was to investigate the utility of blood-basedbiomarkers of amyloid, tau, and neurodegeneration for (i) screening, (ii)enrichment, and (iii) tracking response to treatment in clinical trials of Alzheimer’sdisease.Methods: Longitudinal, participant-level data used in these studies was drawn fromthe Swedish BioFINDER study and the ADNI study. LÄS MER
2. The inflammatory response to traumatic brain injury and a potential cure for it
Sammanfattning : .... LÄS MER
3. IgA Nephropathy – Mucosal Immunity and Treatment Options
Sammanfattning : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. LÄS MER
4. Depression in teenagers and young adults : foundational studies of the new treatment paradigm TARA: Training for Awareness, Resilience, and Action
Sammanfattning : Introduction: Depression in adolescents and young adults is an increasing global health concern and available treatments are not convincingly effective. It is therefore important to develop and test novel treatments to improve treatment outcomes. LÄS MER
5. Glutamate for metabolic intervention in coronary surgery : with special reference to the GLUTAMICS-trial
Sammanfattning : Myocardial ischemia is a major cause of postoperative heart failure and adverse outcome in coronary artery bypass graft surgery (CABG). Conventional treatment of postoperative heart failure with inotropic drugs may aggravate underlying ischemic injury. LÄS MER