Sökning: "Clinical Cancer Trials"

Visar resultat 1 - 5 av 197 avhandlingar innehållade orden Clinical Cancer Trials.

1. 1. Patients in Clinical Cancer Trials : Understanding, Motivation and Hope

   Författare :Tove Godskesen; Ulrik Kihlbom; Peter Nygren; Karin Nordin; Peter Strang; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; adults; clinical trials; phase 1 trials; phase 3 trials; patient information; patient education; informed consent; hope;

   Sammanfattning : The overall aim of this thesis was to study participants' understanding of clinical cancer trials, and their motivation for participation. Of particular interest was the question of whether the patients hoped for a cure resulting from the trial. LÄS MER

3. 2. Someone has to tell them : exploring hereditary cancer risk disclosure in Sweden

   Författare :Carolina Hawranek; Anna Rosén; Senada Hajdarevic; Beatrice S. Melin; Barbro Numan Hellquist; Maria Katapodi; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; hereditary cancer; prevention; family disclosure; family communication; cancer worry; risk information; at-risk relatives; cascade testing; genetic counselling; public opinion; Oncology; onkologi; Genetics; genetik;

   Sammanfattning : Summary in EnglishBackground: An awareness of hereditary susceptibility for breast, ovarian and colorectal cancer in high-risk families enables targeted cancer prevention. A discovered hereditary risk in one family member (proband) may thus be important for several members of that family. LÄS MER

4. 3. Factors Influencing Selection of Treatment for Colorectal Cancer Patients

   Författare :Nina Cavalli-Björkman; Bengt Glimelius; Jonas Bergh; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; socioeconomic status; clinical trials; education level; family support; living alone; patient-physician interaction; Oncology; Onkologi;

   Sammanfattning : In Sweden and elsewhere there is evidence of poorer cancer survival for patients of low socioeconomic status (SES), and in some settings differences in treatment by SES have been shown.The aim of this thesis was to explore factors which influence cancer treatment decisions, such as knowledge reaped from clinical trials, patient-related factors, and physician-related factors. LÄS MER

5. 4. Predictive markers for tamoxifen response in primary breast cancer

   Författare :Maria Stendahl; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; Cytologi; onkologi; prognosis; Cytology; oncology; cancerology; predictive marker; p27; cyclin D1; tamoxifen; PR; breast cancer; ER; pathological anatomy; Patologi allmän ; patologisk anatomi;

   Sammanfattning : It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. LÄS MER

7. 5. Comparative Treatment Planning in Radiotherapy and Clinical Impact of Proton Relative Biological Effectiveness

   Författare :Jonas Johansson; Bengt Glimelius; Anders Montelius; Tony Lomax; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Radiotherapy; Comparative studies; Breast cancer; hypopharyngeal cancer; rectal cancer; Proton RBE; Onkologi; Oncology; Onkologi;

   Sammanfattning : The development of new irradiation techniques is presently a very active field of research with increased availability of more sophisticated modalities such as intensity modulated photons (IMRT), protons and light ions. The primary aim of this work is to evaluate if the dose-distributions using IMRT and protons contribute to clinical advantages. LÄS MER