Sökning: "Claudin"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet Claudin.

1. 1. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

   Författare :Yihong Zhu; Göteborgs universitet; []
   Nyckelord :junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

   Sammanfattning : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. LÄS MER

3. 2. Cell adhesion proteins in different invasive patterns of colon carcinomas : a morphometric and molecular genetic study

   Författare :Victoria Hahn-Strömberg; Lennart Franzén; Richard Palmqvist; Örebro universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; colon carcinoma; growth pattern; tight junction; Complexity Index; cell adhesion; E-cadherin; Beta-catenin; Occludin; Claudin.; Medicine; Medicin; Biomedicin; Biomedicine;

   Sammanfattning : Colorectal carcinoma is the second most common type of cancer in both men and women in Sweden. Cancer of the colon and rectum are often considered together and their ten year survival rate is approximately 50 – 60 % depending on sex and location. LÄS MER

4. 3. An integrative strategy for targeted evaluation of biomarker expression in non-small cell lung cancer

   Författare :Johanna Mattsson; Patrick Micke; Johan Botling; Fredrik Pontén; Åslaug Helland; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-small cell lung cancer; prognostic biomarkers; predictive biomarkers; immunohistochemistry; gene expression; COX-2; claudin; ALK; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Despite improvements in therapy, the prognosis for non-small cell lung cancer (NSCLC) patients remains poor, and cure is only possible in localized tumors after surgical resection. A new generation of targeted cancer drugs has led to the expectation that lung cancer therapy can be significantly improved, but these drugs are today only an option in a small subset of NSCLC patients, and their effect is temporary. LÄS MER

5. 4. Coeliac Disease in Childhood : On the Intestinal Mucosa and the Use of Oats

   Författare :Elisabet Hollén; Karl-Eric Magnusson; Marie-Louise Hammarström; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiaki; havre; avenin; anti-aveninantikroppar; NO; tight junctions; occludin; claudin; Medical microbiology; Medicinsk mikrobiologi;

   Sammanfattning : Celiaki, eller glutenintolerans, är en av våra vanligaste kroniska sjukdomar i barnaåren. Sjukdomen orsakar en kraftig inflammation i tunntarmens slemhinna efter intag av glutenhaltig föda hos personer med ärftlig benägenhet att utveckla celiaki. En frisk tarm är kraftigt veckad för att öka ytan för upptag av näringsämnen. LÄS MER

7. 5. Ovarian Carcinoma - Early Detection and Prognostication

   Författare :Laura Martin de la Fuente; Bröst- och ovarialcancer; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-grade serous ovarian carcinoma; early detection markers; pre-diagnostic cervical sample; copy number alterations CNA ; copy number signatures; Claudin-4; immune cell infiltration; PD-1 PD-L1 pathway;

   Sammanfattning : .... LÄS MER