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Visar resultat 1 - 5 av 35 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Living with Long-Term Pain after a Stroke

   Författare :Marita Widar; Gerd Ahlström; Anna-Christina Ek; Fannie Gaston-Johansson; Linköpings universitet; []
   Nyckelord :stroke; central pain; chronic pain; neuropathic pain; nociceptive pain; shoulder; pain; tension-type headache; pain assessment; disability; activities of daily living; coping; health-related quality of life; mood; caring; MEDICINE; MEDICIN;

   Sammanfattning : The general aim of this thesis was to classify and describe long-term pain two years after a stroke and to describe the experiences of pain, and the consequences it has on the persons’ lives. The studies were conducted from a multidimensional perspective on pain, combining quantitative and qualitative methods. LÄS MER

3. 2. Pain analysis : A study in patients with chronic low back pain or fibromyalgia

   Författare :John Sörensen; Alf Udén; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Chronic low back pain (CLBP} and fibromyalgia (FM} are two common chronic pain conditions in which the pain processing mechanisms are not well understood. To identify the types of pain, we used different intravenous {t.v. LÄS MER

4. 3. Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids

   Författare :Anne-Li Lind; Torsten Gordh; Masood Kamali-Moghaddam; Jonas Bergquist; Eva Kosek; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chronic pain; neuropathic pain; lumbar radicular pain; amyotrophic lateral sclerosis; radiculopathy; fibromyalgia; pathophysiology; spinal cord stimulation; mechanism of action; disc herniation; cerebrospinal fluid; plasma; biomarker; human; protein; chemokines; cytokines; inflammation; neuroinflammation; mass spectrometry; proximity ligation assay; proximity extension assay; antibody suspension bead array; protein profiling; molecular medicine; personalized medicine; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. LÄS MER

5. 4. Proteomics Studies of Subjects with Alzheimer’s Disease and Chronic Pain

   Författare :Payam Emami Khoonsari; Kim Kultima; Martin Ingelsson; Magnus Wetterhall; Ann Brinkmalm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioinformatics; microservices; biomarkers; Alzheimer s disease; chronic pain; fibromyalgia; neuropathic pain; spinal cord stimulation; cloud computing; proteomics; metabolomics; software; workflows; data analysis; mass spectrometry; Bioinformatics; Bioinformatik; Neurology; Neurologi; Geriatrics; Geriatrik;

   Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disease and the major cause of dementia, affecting more than 50 million people worldwide. Chronic pain is long-lasting, persistent pain that affects more than 1.5 billion of the world population. LÄS MER

7. 5. Interactions with pain-related systems - Towards new electrical treatments for chronic pain

   Författare :Matilde Forni; NanoLund: Centre for Nanoscience; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High definition brain stimulation; Periaqueductal gray matter; Pain systems; Pain models;

   Sammanfattning : Background. Persistent intolerable pain is still an unsolved issue with a huge socioeconomic impact. To develop appropriate treatments, it is crucial to understand the complex mechanisms underlying pain and how they change during sustained pain stimuli or during pathological conditions. LÄS MER