Sökning: "Christopher Winston Uhde"

Hittade 1 avhandling innehållade orden Christopher Winston Uhde.

1. 1. Mechanisms of cell diversification

   Författare :Christopher Winston Uhde; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cell identity and function is determined by the intrinsic wiring of the gene regulatory network that endows progenitors with the competence to respond appropriately to extrinsic cues in a spatiotemporally-dependent manner. One such class of cues, morphogens, instruct cells in their identity by virtue of a concentration gradient, but how this is interpreted at gene regulatory levels to result in sharp and robust boundaries of gene expression is poorly understood. LÄS MER