Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Molecular principles of protein stability and protein-protein interactions

    Författare :Christofer Lendel; Per-Åke Nygren; Christopher M. Dobson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; affibody; binding thermodynamics; induced fit; molten globule; NMR spectroscopy; protein engineering; protein-protein interactions; protein stability; protein structure.; Structural biochemistry; Strukturbiokemi;

    Sammanfattning : Proteins with highly specific binding properties constitute the basis for many important applications in biotechnology and medicine. Immunoglobulins have so far been the obvious choice but recent advances in protein engineering have provided several novel constructs that indeed challenge antibodies. LÄS MER

  3. 2. Preparation and Application of Functionalized Protein Fibrils

    Författare :Fredrik Bäcklund; Niclas Solin; Olle Inganäs; Christofer Lendel; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Many proteins have an innate ability to self-assemble into fibrous structures known as amyloid fibrils. From a material science perspective, fibrils have several interesting characteristics, including a high stability, a distinct shape and tunable surface properties. LÄS MER

  4. 3. Integrative structural biology of protein fibers: Spider silk and beta-lactoglobulin nanofibrils

    Författare :Danilo Hirabae De Oliveira; My Hedhammar; Christofer Lendel; Martin Humenik; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Spider Silk; Spidroin; fiber protein structure; amyloid-like fibers; Beta-lactoglobulin; Spindel silke; Spidroin; fiberproteinstruktur; amyloidliknande fibrer; Betalaktoglobulin; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins found in nature offer a vast range of exceptional materials, including high-performancebiopolymers such as spider silks and whey protein nanofibrils. Fibrous proteins possess immensepotential for developing novel materials suited for various applications, such as medicalbiomaterials or industrial products. LÄS MER

  5. 4. Membrane interactions of glycosyltransferases

    Författare :Jobst Liebau; Lena Mäler; Christofer Lendel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipid; bicelle; glycosyltransferase; NMR; Biophysics; biofysik;

    Sammanfattning : Many important biological processes occur near or in membranes. The role of membranes is not merely confined to compartmentalization, they also form the matrix for membrane associated proteins and are of functional importance. Membrane associated proteins on the other hand require specific membrane properties for proper function. LÄS MER

  7. 5. Materials Based on Protein Nanofibrils

    Författare :Xinchen Ye; Mikael S. Hedenqvist; Christofer Lendel; Richard T. Olsson; Jonny Blaker; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; protein nanofibrils; whey protein; hydrogel; film; microfibre; protein structure; mechanical properties;

    Sammanfattning : Protein nanofibrils (PNFs) prepared from whey protein isolate (WPI) at low pH and elevated temperature were processed into materials, i.e. hydrogels, films, foams, and fibres, for different applications where they could potentially be sustainable alternatives to petroleum-based polymers. LÄS MER