Sökning: "Christina Patlaka"

Hittade 1 avhandling innehållade orden Christina Patlaka.

1. 1. Tartrate resistant acid phosphatase 5a : a potential regulator of adipocyte cell number and differentiation in white adipose tissue

   Författare :Christina Patlaka; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Tartrate-resistant acid phosphatase (TRAP) exists in two isoforms, TRAP 5a which is monomeric and TRAP 5b which is a dimer generated by proteolytic cleavage of TRAP 5a, that exhibit different functions and localizations. TRAP 5a is expressed by adipose tissue macrophages and secreted into the extracellular environment and has been shown to lead to hyperplastic insulin-sensitive obesity when over-expressed in mice. LÄS MER