Sökning: "Christiansson Lisa"

Hittade 1 avhandling innehållade orden Christiansson Lisa.

1. 1. Myeloid-Derived Suppressor Cells and Other Immune Escape Mechanisms in Chronic Leukemia

   Författare :Lisa Christiansson; Angelica S I Loskog; Ulla Olsson-Strömberg; Andreas Lundqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic myeloid leukemia; myeloid-derived suppressor cells; sCD25; tyrosine kinase inhibitors; multiplex protein quantification; Medical Science; Medicinsk vetenskap;

   Sammanfattning : Chronic myeloid leukemia (CML) is characterized by the Philadelphia chromosome, a minute chromosome that leads to the creation of the fusion gene BCR/ABL and the transcription of the fusion protein BCR/ABL in transformed cells. The constitutively active tyrosine kinase BCR/ABL confers enhanced proliferation and survival on leukemic cells. LÄS MER