Sökning: "Christian Scharenberg"

Hittade 1 avhandling innehållade orden Christian Scharenberg.

  1. 1. The mutational landscape and microenvironment in myelodysplastic syndromes with deletion of chromosome 5q

    Författare :Christian Scharenberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Myelodysplastic Syndromes (MDS) with deletion of chromosome 5q (del(5q) are malignant bone marrow disorders characterized by macrocytic anemia, chronic transfusion dependency and an increased risk of progression to acute myeloid leukemia. A high proportion of patients with lower-risk del(5q) myelodysplastic syndromes will respond to lenalidomide treatment, but more than 40% of patients have progressed to acute leukemia five years after starting treatment. LÄS MER