Sökning: "Chondrogenesis"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet Chondrogenesis.

  1. 1. Differentiation of Human Dermal Fibroblasts and Applications in Tissue Engineering

    Författare :Pehr Sommar; Gunnar Kratz; Thomas Hansson; Anders Lindahl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Engineering; Human Dermal Fibroblasts; Differentiation; Adipogenesis; Chondrogenesis; Endotheliogenesis; Osteogenesis; Plastic surgery; Plastikkirurgi;

    Sammanfattning : Tissue engineering applies principles of biology and engineering to the development of functional substitutes for damaged or lost tissues. Tools for the neo-generation of tissue in tissue engineering research include cells, biomaterials and soluble factors. LÄS MER

  3. 2. The role of estrogen in growth plate chondrogenesis

    Författare :Ola Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Overall body proportion is determined by the size of the skeleton, which in turn is determined by the rate and duration of longitudinal bone growth. Longitudinal bone growth occurs at the growth plate and is regulated by a variety of hormones and growth factors. LÄS MER

  4. 3. Effects of proteasome inhibitors on chondrogenesis and linear bone growth

    Författare :Emma Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Linear bone growth occurs at the growth plate, a thin layer of cartilage between the epiphysis and metaphysis of long bones. In the growth plate, resting/stem-like chondrocytes divide and generate the highly proliferative chondrocytes, which further differentiate into the enlarged hypertrophic form before being substituted by bone, a process called endochondral ossification. LÄS MER

  5. 4. Effect of shock wave therapy on longitudinal bone growth and growth plate cartilage

    Författare :Sowmya Ramesh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aim: The overall aim of this thesis was to investigate the potential for radial shock wave treatment (rSWT) to regulate growth plate chondrogenesis and longitudinal bone growth. It was based on the hypothesis that the effects are dose-dependent in a bimodal response pattern where low-energy rSWT will increase chondrocyte proliferation/hypertrophy, and thereby bone growth, while high frequency/energy rSWT will induce chondrocyte apoptosis and thereby, premature growth plate closure. LÄS MER

  7. 5. Effects of growth factors on chondrocyte proliferation and differentiation

    Författare :Caroline Edwall-Arvidsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Growth plate cartilage; limb buds; growth factors; proliferation; differentiation; collagens; c-fos; ALP;

    Sammanfattning : Longitudinal bone growth is regulated at the level of growth plate chondrocytes by circulating or locally produced hormones and growth factors. Present investigation focused on the effects of growth hormone (GH) and growth factors on chondrocyte proliferation and differentiation during pre- and postnatal cartilage development. LÄS MER