Sökning: "Choline Acetyltransferase"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden Choline Acetyltransferase.
1. Cholinergic and dopaminergic aspects of dementia in Parkinson's disease: postmortem neuropathological findings and modeling of cognitive dysfunction in rodents
Sammanfattning : Motor symptoms are currently considered the first clinical hallmark of Parkinson’s disease (PD). They develop as a result of dopamine loss in the striatum, subsequent to the progressive neurodegeneration of dopamin- ergic neurons in the substantia nigra. LÄS MER
2. Mechanisms of cell type-specific gene transcription : studies on the choline acetyltransferase gene
Sammanfattning : Choline acetyltransferase (ChAT) is the enzyme synthesizing the neurotransmitter acetylcholine. Previous studies from our laboratory on the regulation of the cholinergic phenotype have suggested the presence of regulatory elements in the ChAT gene controlling accurate time- and cell-specific expression. LÄS MER
3. Cholinergic mechanisms in the spinal cord : topographical localizations of choline acetyltransferase and neuroreceptors and their changes in amyotrophic lateral sclerosis
Sammanfattning : .... LÄS MER
4. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain
Sammanfattning : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). LÄS MER
5. Analysis of organic and inorganic arsenicals in biological material
Sammanfattning : An analytical method for measurement of the urinary metabolites of inorganic arsenic is presented. Increased concentrations of urinary metabolites of inorganic arsenic are indicative of occupational exposure. Organoarsenic compounds in the urine from seafood intake do not affect the analytical results. LÄS MER