Avancerad sökning

Visar resultat 1 - 5 av 38 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Ion channel control of phasic insulin secretion

    Författare :Xingjun Jing; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phasic insulin secretion; Diabetes; pancreatic β-cells; ClC chloride channel; exocytosis; CaV channel;

    Sammanfattning : Glucose-stimulated insulin secretion exhibits a biphasic pattern. The mechanism underling biphasic insulin secretion is not fully understood, but consensus exists that an elevation in [Ca2+]i is required for both first- and second-phase insulin secretion. LÄS MER

  3. 2. Chloride Channels and Brown Fat Cells

    Författare :Victor Sabanov; Jan Nedergaard; Bernd Nilius; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chloride channel; BAPTA; EGTA; Ca; Animal physiology; Zoofysiologi;

    Sammanfattning : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. LÄS MER

  4. 3. Chloride transport and inflammation in cystic fibrosis airways

    Författare :Georgia Varelogianni; Godfried Roomans; Marie Johannesson; Ólafur Baldersson; Örebro universitet; []
    Nyckelord :Cystic fibrosis; CFTR; chloride efflux; N-acetylcysteine; ambroxol; duramycin; Nod-like receptors; cytokines; Medicin; Medicine;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. LÄS MER

  5. 4. Molecular regulation of epithelial tube size

    Författare :Erika Tång Hallbäck; Göteborgs universitet; []
    Nyckelord :Drosophila; tube shape; trachea; chitin; luminal matrix; epithelial tubes; morphogenesis; chloride channel; subapical actin;

    Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER

  7. 5. Functional Aspects of Epithelia in Cystic Fibrosis and Asthma

    Författare :Zhanna Servetnyk; Godfried Roomans; Michael Wilschansky; Uppsala universitet; []
    Nyckelord :Cell biology; cystic fibrosis; CFTR; chloride transport; airway epithelium; sweat gland; asthma; corticosteroids; montelukast; Cellbiologi;

    Sammanfattning : The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease. LÄS MER