Sökning: "Chiral Separation"

Visar resultat 16 - 20 av 40 avhandlingar innehållade orden Chiral Separation.

  1. 16. Determination of the Environmental Fate of Drug Substances and the Matrix Effects of Complex Samples in SFC/ESI-MS

    Författare :Alfred Haglind; Curt Pettersson; Mikael Hedeland; Torbjörn Arvidsson; Deirdre Cabooter; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SFC-MS; matrix effect; ion cluster; Supercritical fluid chromatography; ESI; chiral separation; transformation products; LC-QToF; wetland microcosms; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Awareness of the potential problems caused by drug compounds in the environment has increased over the last decade, both among researchers and with the public. This thesis describes the development of analytical methods and their application to wetlands constructed for purification of wastewater from e.g. drug compounds. LÄS MER

  2. 17. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods

    Författare :Javier Zurita; Leopold Ilag; Ulrika Nilsson; Margareta Törnqvist; Natalia Tretyakova; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amino acids; LC MS; fixed-charge derivatization; BMAA; chiral separation; pheromones; arctic aerosols; serum albumin adducts; benzo[a]pyrene diol epoxides; high-resolution MS; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). LÄS MER

  3. 18. Optimized chiral separation of protein amino acids and dipeptides by capillary electrophoresis

    Författare :Hong Wan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 19. Development and Validation of Methods for Characterization of Multi-Component Systems in Preparative LC

    Författare :Robert Arnell; Torgny Fornstedt; Andreas Seidel-Morgenstern; Uppsala universitet; []
    Nyckelord :Analytical chemistry; Liquid chromatography; Preparative LC; Chiral LC; Multi-component LC; Adsorption isotherm; Tracer-pulse method; Inverse method; Inverse method on plateaus; Peak deformations; Chiral drug-protein interactions; Analytisk kemi;

    Sammanfattning : This thesis concerns the development and validation of methods for characterization of multi-component preparative LC systems. Measurements of competitive adsorption isotherms are performed to gain detailed information about the interactions inside the chromatography column. LÄS MER

  5. 20. Optimization of liquid chromatographic separation on chiral stationary phases for enantioselective assay of drugs in biological samples

    Författare :Karin Balmér; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER