Sökning: "Chiral Separation"

Visar resultat 1 - 5 av 37 avhandlingar innehållade orden Chiral Separation.

  1. 1. Aspects of Optimisation of Separation of Drugs by Chemometrics

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Valérie Harang; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; optimisation; separation; chemometrics; high performance liquid chromatography; electrodriven techniques; microemulsion electrokinetic chromatography; statistical experimental design; molecular modelling; chiral separation; cellobiohydrolase; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi;

    Sammanfattning : Statistical experimental designs have been used for method development and optimisation of separation. Two reversed phase HPLC methods were optimised. LÄS MER

  2. 2. New Techniques for Chiral Separations

    Detta är en avhandling från Karlstad : Karlstads universitet

    Författare :Jeanette Olsson; Karlstads universitet.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; analytical chemistry; chiral separation; GC; CE; CEC; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Kemi; Chemistry;

    Sammanfattning : Gas chromatography (GC) has been utilized for the study of enantiomer resolution of the atropisomers of PCBs, o,p´-DDD and o,p´-DDT. Different substituents and concentrations of cyclodextrin, capillary dimensions and type of stationary phase films have been investigated to achieve the resolution of as many of the atropisomers on one column as possible. LÄS MER

  3. 3. Chiral Separation of Amines by Non-Aqueous Capillary Electrophoresis using Low Molecular Weight Selectors

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ylva Hedeland; Uppsala universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pharmaceutical chemistry; Chiral Separation; Non-Aqueous Capillary Electrophoresis; Enantioresolution; Electro-osmotic Flow; Pharmaceuticals; Enantiomeric Amines; Low Molecular Weight Selector; Farmaceutisk kemi; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry; Analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Three chiral selectors (diketogulonic acid, benzoxycarbonylglycylproline and ketopinic acid) have been introduced for enantioseparation of pharmacologically active amines in non-aqueous capillary electrophoresis. The use of organic solvents, instead of aqueous buffers in the background electrolyte facilitated ion-pair formation between the analytes and the chiral selectors. LÄS MER

  4. 4. Separation of Pharmaceuticals by Capillary Electrophoresis using Partial Filling and Multiple-injections

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Henrik Lodén; Uppsala universitet.; [2008]
    Nyckelord :Capillary Coating; Chiral Separation; Enantiomers; Mass-spectrometric Detection; Method Validation; Multiple-injection Capillary Zone Electrophoresis; Non-aqueous Capillary Electrophoresis; Organic Solvents; Pharmaceutical Analysis; Quantitative Analysis;

    Sammanfattning : Different multiple-injection methodologies and the partial filling technique (PFT) have been utilized for separation of pharmaceuticals by capillary elec-trophoresis.In multiple-injection capillary zone electrophoresis (MICZE), the samples and all standards, used for construction of the calibration curve, are analyzed within a single run. LÄS MER

  5. 5. Molecular Imprinting Technology. Design and Recognition Properties of Antibody/Receptor Mimics

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Olof Ramström; [1996]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Template Polymerisatio; Steroid; Receptor; Racemic Resolution; Polymer; Molecular Recognition; Molecular Imprinting; Enantiomeric Separation; de novo Design; Chromatography; Chiral Stationary Phase; Chiral Recognition; Biorecognition; Antibody; Biomimetic; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik;

    Sammanfattning : Molecular imprinting technology is derived from the concept of creating designed recognition sites in macromolecular matrices by means of template polymerisation. Molecularly imprinted polymers are able to mimic recognition in natural binding events, such as antibody-antigen and receptor-ligand interactions. LÄS MER