Sökning: "Chemical risk information"

Visar resultat 6 - 10 av 107 avhandlingar innehållade orden Chemical risk information.

  1. 6. In silico tools in risk assessment : of industrial chemicals in general and non-dioxin-like PCBs in particular

    Författare :Mia Stenberg; Patrik Andersson; Miriam Jacobs; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; industrial chemicals; in silico tools; molecular descriptors; non-dioxin-like PCBs; partial least-squares PLS ; principal component analysis PCA ; quantitative structure-activity relationship QSAR ; REACH; risk assessment RA ; statistical molecular design; structure-activity relationship SAR ;

    Sammanfattning : Industrial chemicals in European Union produced or imported in volumes above 1 tonne annually, necessitate a registration within REACH. A common problem, concerning these chemicals, is deficient information and lack of data for assessing the hazards posed to human health and the environment. LÄS MER

  2. 7. Metal Particles – Hazard or Risk? Elaboration and Implementation of a Research Strategy from a Surface and Corrosion Perspective

    Författare :Klara Midander; Inger Odnevall Wallinder; Sannakaisa Virtanen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ferro-chromium alloy; metal particles; bioaccessibility; chemical speciation; dermal contact; surface oxide; in-vitro testing; chemical speciation; cu; copper; comet assay; intracellular; ultrafine; in vitro; A549; cytotoxicity; DNA damage; nanoparticles; particle characterization; artificial sweat; nickel release; nickel powder particles; particle loadings; release kinetics; surface area; copper release; powder particles; synthetic body fluids; simulation of interstitial lung conditions; skin contact; metal release; stainless steel; particles; test method; Surface and colloid chemistry; Yt- och kolloidkemi; Analytical chemistry; Analytisk kemi; Spectroscopy; Spektroskopi;

    Sammanfattning : Do metal particles (including particles of pure metals, alloys, metal oxides and compounds) pose a hazard or risk to human health? In the light of this question, this thesis summarizes results from research conducted on metal particles, and describes the elaboration and implementation of an in vitro test methodology to study metal release from particles through corrosion and dissolution processes in synthetic biological media relevant for human exposure through inhalation/ingestion and dermal contact. Bioaccessible metals are defined as the pool of released metals from particles that potentially could be made available for absorption by humans or other organisms. LÄS MER

  3. 8. Managing chemical risks in the EU : Data use and new approaches for decision-making

    Författare :Flora Borchert; Marlene Ågerstrand; Annemarie van Wezel; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; risk management; decision-making; REACH; data use; essential use concept; Chemical Strategy for Sustainability; plant protection products; environmental risk assessment; Environmental Sciences; miljövetenskap;

    Sammanfattning : Man-made chemicals benefit our living standards, but exposure to the (most) harmful ones can lead to negative, irreversible effects on human health and the environment. The risk management of harmful chemicals aims to protect human health and the environment from unacceptable risks. LÄS MER

  4. 9. Formation of Skin Sensitizers from Fragrance Terpenes via Oxidative Activation Routes. Chemical analysis, Structure Elucidation and Experimental Sensitization Studies

    Författare :Lina Hagvall; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The work presented in this thesis emphasizes the importance of considering oxidative activation in the toxicity assessment of fragrance chemicals. Compounds without contact allergenic properties can be activated either via autoxidation in contact with air or via cutaneous metabolism to reactive products which can cause contact allergy. LÄS MER

  5. 10. Leaching of Polycyclic Aromatic Hydrocarbons Using a Column Method

    Författare :Anja Enell; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemiteknik och kemisk teknologi; Naturvetenskap; Chemical technology and engineering; Natural science; Miljöstudier; Environmental studies; coal tar; PAHs; desorption; soil; combustion residues; remediation; availability;

    Sammanfattning : Polycyclic aromatic hydrocarbons (PAHs) are a group of organic pollutants of great environmental concern, due to their toxicity, carcinogenicity and long persistence in the environment. To determine the potential risk associated with PAHs released from contaminated soil or waste materials, knowledge is required on the leachable concentrations of PAHs and the amounts available for release. LÄS MER